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Sigma-Aldrich

N6-炔丙基-ATP 钠盐

别名:

(N6pATP) 钠盐, N6-炔丙基-腺苷-5’-三磷酸盐 钠盐

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About This Item

经验公式（希尔记法）:
C13H18N5O13P3 · xNa+
分子量:
545.23 (free acid basis)
分類程式碼代碼:
12352200
PubChem物質ID:
329769102
NACRES:
NA.22

化驗

≥95% (HPLC)

品質等級

200

形狀

solid

反應適用性

reaction type: click chemistry

溶解度

10 mM Tris-HCl, pH 7.5: soluble

運輸包裝

wet ice

儲存溫度

−20°C

SMILES 字串

O[C@@H]([C@H]1O)[C@@H](COP(O)(OP(O)(OP(O)(O)=O)=O)=O)O[C@@H]1N2C=NC3=C2N=CN=C3NCC#C

InChI

1S/C13H18N5O13P3/c1-2-3-14-11-8-12(16-5-15-11)18(6-17-8)13-10(20)9(19)7(29-13)4-28-33(24,25)31-34(26,27)30-32(21,22)23/h1,5-7,9-10,13,19-20H,3-4H2,(H,24,25)(H,26,27)(H,14,15,16)(H2,21,22,23)/t7-,9-,10-,13?/m1/s1

InChI 密鑰

MUOIWXPACQCYQC-RJNFYWFKSA-N

相关类别

應用

N6-炔丙基-ATP适用于蛋白质的体外AMPylation以及RNA的体外聚腺苷酸化。可以使用Cu(I)催化的点击化学方法处理所得的炔烃官能化的蛋白质或RNA，以连接叠氮化物标记的分子。这提供了诸如引入用于纯化任务的生物素基团，引入用于检测的荧光基团或与其他叠氮化物官能化的生物分子交联的选择。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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Protein AMPylation is an emerging post-translational modification, which plays key roles in bacterial pathogenesis and cell biology. Enzymes with AMPylation activity, referred to as AMPylators, have been identified in several bacterial pathogens and eukaryotes. To facilitate the study of this
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A versatile "clickable" nucleoside: Metabolic labeling of cells is useful in studying the dynamics of biological molecules. N(6) pA can be utilized by all three mammalian RNA polymerases, as well as poly(A) polymerase. Because of its alkyne modification, RNA labeled
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