772828

5-Norbornene-2-endo-acetic acid

• 别名: Bicyclo[2.2.1]hept-5-en-2-ylacetic acid, Norbornene acetic acid
• 经验公式（希尔记法）: C₉H₁₂O₂
• CAS号: 825-71-8
• 分子量: 152.19
• 分類程式碼代碼: 12352106
• PubChem物質ID: 329766608
• NACRES: NA.22

属性

• 形狀: liquid
• 品質等級: 100
• 反應適用性: reaction type: click chemistry; reagent type: linker
• 折射率: n20/D 1.495
• 密度: 1.124 g/mL at 25 °C
• 官能基: carboxylic acid
• SMILES 字串: OC(CC1C[C@@H]2C=C[C@H]1C2)=O
• InChI: 1S/C9H12O2/c10-9(11)5-8-4-6-1-2-7(8)3-6/h1-2,6-8H,3-5H2,(H,10,11)/t6-,7+,8?/m1/s1
• InChI 密鑰: HRVGJQMCNYJEHM-KVARREAHSA-N

说明

應用

Carboxylic acid functionalized norbornene. Carboxylic acid can be used to modify amine containing compounds such as lysine residues on proteins/peptides via standard peptide coupling methods. Norbornene has been shown to react with 1,2,4,5-tetrazines in an inverse electron demand Diels-Alder cycloaddition reaction, which is a bioorthogonal click chemistry reaction demonstrated to be useful in biological imaging applications.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302,H412
• 防範說明: P273 - P301 + P312 + P330
• 危險分類: Acute Tox. 4 Oral - Aquatic Chronic 3
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable