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Merck
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文件

767751

Sigma-Aldrich

2- {2- [2-（2-巯基乙氧基）乙氧基]乙氧基}乙醇

97%

别名:

MEEE, 1-Mercapto-11-hydroxy-3,6,9-trioxaundecane

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About This Item

经验公式（希尔记法）:
C8H18O4S
分子量:
210.29
MDL號碼:
MFCD22574773
分類程式碼代碼:
12352200
PubChem物質ID:
329767336
NACRES:
NA.22

化驗

97%

形狀

liquid

反應適用性

reagent type: cross-linking reagent

折射率

n20/D 1.481

密度

1.098 g/mL at 25 °C

SMILES 字串

OCCOCCOCCOCCS

InChI

1S/C8H18O4S/c9-1-2-10-3-4-11-5-6-12-7-8-13/h9,13H,1-8H2

InChI 密鑰

GKKYNULPAQDGHI-UHFFFAOYSA-N

相关类别

應用

2-{2-[2-(2-Mercaptoethoxy)ethoxy]ethoxy}ethanol may be used in the synthesis of 2-(2-(2-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)ethoxy)ethoxy)ethanol, an nitrobenzoxadiazole (NBD) analog of the anticancer agent 6-((7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)thio)hexan-1-ol (NBDHEX). This analog is a potent glutathione S-transferase (GST) and a potential therapeutic antimelanoma agent with enhanced water solubility and antitumor efficacy when compared to NBDHEX in a study.
  • Oligo-ehtylene glycol of peptides and small molecules (PEGylation)
  • PEG-disulfide formation
  • ultra-thin protein-resistant monolayers
  • Densely packed monolayer and a flexible-hydrophilic oligo ethylene glycol arm for avoiding non-specific adsorption

象形圖

Skull and crossbonesCorrosion
GHS06,GHS05

訊號詞

Danger

危險聲明

H301,H314

危險分類

Acute Tox. 3 Oral - Skin Corr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

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Thiol-functionalized undecagold clusters by ligand exchange: Synthesis, mechanism, and properties.
Woehrle GH & Hutchison JE
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Click and chemically triggered declick reactions through reversible amine and thiol coupling via a conjugate acceptor
Diehl KL, et al.
Nature Chemistry, 8(10) (2016)
Influence of surface functionalization and particle size on the aggregation kinetics of engineered nanoparticles.
Liu J, et al.
Chemosphere, 87(8), 918-924 (2012)
Carbohydrates as the next frontier in pharmaceutical research.
Werz DB & Seeberger PH
Chemistry?A European Journal , 11(11), 3194-3206 (2005)
Thiol functionalized oligo-ethylene glycol, for modification of peptides/small molecules containing thiols or maleimide functional groups
Journal of Materials Chemistry, 9, 1121-1121 (1999)
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