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Merck

730300

Sigma-Aldrich

甲基丙烯酸N-羟琥珀酸亚胺酯

98%

别名:

N-(Methacryloxy)succinimide, N-(Methacryloyloxy)succinimide

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About This Item

经验公式(希尔记法):
C8H9NO4
CAS号:
分子量:
183.16
MDL號碼:
分類程式碼代碼:
12162002
PubChem物質ID:
NACRES:
NA.23

化驗

98%

形狀

solid

mp

101-105 °C

儲存溫度

2-8°C

SMILES 字串

CC(=C)C(=O)ON1C(=O)CCC1=O

InChI

1S/C8H9NO4/c1-5(2)8(12)13-9-6(10)3-4-7(9)11/h1,3-4H2,2H3

InChI 密鑰

ACGJEMXWUYWELU-UHFFFAOYSA-N

一般說明

丙二酸-N-羟基琥珀酰亚胺酯(NHS-MA)属于N-羟基琥珀酰亚胺(NHS)酯类活性单体。常用于通过氨基反应活性的偶联反应修饰生物分子,用于生物偶联、蛋白标记和肽合成领域。 也用作交联剂或连接药物/靶向配体与载体材料的接头分子。

應用

丙二酸-N-羟基琥珀酰亚胺酯可用于:
  • 作为单体经由RAFT聚合反应制备可降解的两亲性双嵌段共聚物微粒,用于低pH值启动的药物递送。NHS-MA可保护药物分子免遭降解,增强其溶解性和药动学特性。
  • 组织工程用聚-ε-己内酯(PCL)支架的表面改性。NHS基团用于偶联不同分子量的壳聚糖。
  • 制备生物相容性聚合物水凝胶用于酶生物燃料电池。水凝胶可用作酶生物电极的酶固定基质。

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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