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化驗
98%
形狀
solid
mp
101-105 °C
儲存溫度
2-8°C
SMILES 字串
CC(=C)C(=O)ON1C(=O)CCC1=O
InChI
1S/C8H9NO4/c1-5(2)8(12)13-9-6(10)3-4-7(9)11/h1,3-4H2,2H3
InChI 密鑰
ACGJEMXWUYWELU-UHFFFAOYSA-N
一般說明
丙二酸-N-羟基琥珀酰亚胺酯(NHS-MA)属于N-羟基琥珀酰亚胺(NHS)酯类活性单体。常用于通过氨基反应活性的偶联反应修饰生物分子,用于生物偶联、蛋白标记和肽合成领域。 也用作交联剂或连接药物/靶向配体与载体材料的接头分子。
應用
丙二酸-N-羟基琥珀酰亚胺酯可用于:
- 作为单体经由RAFT聚合反应制备可降解的两亲性双嵌段共聚物微粒,用于低pH值启动的药物递送。NHS-MA可保护药物分子免遭降解,增强其溶解性和药动学特性。
- 组织工程用聚-ε-己内酯(PCL)支架的表面改性。NHS基团用于偶联不同分子量的壳聚糖。
- 制备生物相容性聚合物水凝胶用于酶生物燃料电池。水凝胶可用作酶生物电极的酶固定基质。
訊號詞
Warning
危險分類
Acute Tox. 4 Inhalation - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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