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677418

Sigma-Aldrich

羟基磷灰石

nanopowder, <200 nm particle size (BET), ≥97%, synthetic

别名:

磷酸钙 三元, 三碱基磷酸钙, 氢氧磷灰石, 磷酸羟胺, 羟基磷酸钙

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About This Item

线性分子式:
[Ca5(OH)(PO4)3]x
CAS号:
12167-74-7
分子量:
502.31
EC號碼:
235-330-6
MDL號碼:
MFCD00010904
分類程式碼代碼:
12352302
PubChem物質ID:
24885371
NACRES:
NA.23

品質等級

100

化驗

≥97%

形狀

nanopowder
solid

表面積

>9.4 m2/g

粒徑

<200 nm (BET)

mp

1100 °C (lit.)

SMILES 字串

[Ca++].[Ca++].[Ca++].[Ca++].O[Ca+].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O

InChI

1S/5Ca.3H3O4P.H2O/c;;;;;3*1-5(2,3)4;/h;;;;;3*(H3,1,2,3,4);1H2/q5*+2;;;;/p-10

InChI 密鑰

XYJRXVWERLGGKC-UHFFFAOYSA-D

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相关类别

一般說明

羟基磷灰石（HA）属于钙磷灰石家族， 在结构和化学成分上与天然骨相似。它可以 通过化学沉淀法、水热法、静电纺丝法和 自传播燃烧法等多种方法制备。由于其生物活性和生物相容性， 它被广泛用作骨再生的植入材料、 药物载体和基因传递系统。

應用

纳米羟基磷灰石颗粒具有缓慢的原位生物降解、良好的骨导电性和骨诱导能力，可用于制备骨组织工程材料。

聚(4-苯乙烯磺酸钠)修饰的羟基磷灰石纳米颗粒可作为万古霉素的药物载体。羟基磷灰石纳米颗粒可控制支架植入体内后抗生素的释放。

多孔羟基磷灰石微球对重金属具有较高的吸附能力，可用于重金属污染水体的处理。

特點和優勢

  • 生物活性和生物相容性
  • 机械强度好
  • 多孔结构
  • 骨传导和骨整合特性

法律資訊

Engi-Mat公司产品。

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

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分析证书(COA)

Lot/Batch Number
MKCQ2685
MKCN9004
MKCM1889
MKCK9555
MKCK8172

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Sang-Soo Kim et al.
Biomaterials, 27(8), 1399-1409 (2005-09-20)
Biodegradable polymer/bioceramic composite scaffolds can overcome the limitations of conventional ceramic bone substitutes such as brittleness and difficulty in shaping. However, conventional methods for fabricating polymer/bioceramic composite scaffolds often use organic solvents (e.g., the solvent casting and particulate leaching (SC/PL)
Michiko Sato et al.
Biomaterials, 27(11), 2358-2369 (2005-12-13)
In order to improve orthopedic implant performance, the objective of this in vitro study was to synthesize nanocrystalline hydroxyapatite (HA) powders to coat titanium. HA was synthesized through a wet chemical process. The precipitated powders were either sintered at 1100
Influence of temperature, ripening time and calcination on the morphology and crystallinity of hydroxyapatite nanoparticles.
Pang YX, et al.
J. Eur. Ceram. Soc., 23(10), 1697-1704 (2003)
Hydroxyapatite nanoparticles: a review of preparation methodologies
Ferraz MP, et al.
Journal of Applied Biomaterials & Biomechanics : JABB, 2(2), 74-80 (2004)
Liam M Grover et al.
Biomaterials, 34(28), 6631-6637 (2013-06-12)
Pyrophosphate ions are both inhibitors of HA formation and substrates for phosphatase enzymes. Unlike polyphosphates their hydrolysis results simultaneously in the complete loss of mineral formation inhibition and a localised elevation in orthophosphate ion concentration. Despite recent advances in our
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