676403

(R,R)-(–)-2,3-双(叔丁基甲基膦基)喹喔啉

≥95%

• 别名: (R) QuinoxP^®
• 经验公式（希尔记法）: C₁₈H₂₈N₂P₂
• CAS号: 866081-62-1
• 分子量: 334.38
• MDL號碼: MFCD10565649
• 分類程式碼代碼: 12352005
• PubChem物質ID: 24884852
• NACRES: NA.22

属性

• 品質等級: 100
• 化驗: ≥95%
• 形狀: solid
• mp: 100-104 °C
• 官能基: phosphine
• SMILES 字串: CP(c1nc2ccccc2nc1P(C)C(C)(C)C)C(C)(C)C
• InChI: 1S/C18H28N2P2/c1-17(2,3)21(7)15-16(22(8)18(4,5)6)20-14-12-10-9-11-13(14)19-15/h9-12H,1-8H3/t21-,22-/m0/s1
• InChI 密鑰: DRZBLHZZDMCPGX-VXKWHMMOSA-N

说明

一般說明

(R,R)-(-)-2,3-Bis(tert-butylmethylphosphino)quinoxaline is an air-stable C₂-symmetric P-stereogenic phosphine ligand.

應用

Air-Stable and Highly Efficient Chiral Ligands

在合成转化反应中显示高水平手性控制的高效配体，转化反应范围从金属催化芳基硼酸 1,4-加成到烷基化的开环到不对称氢化。

特點和優勢

Advantages of the QuinoxP* Ligands:

• It is not oxidized nor epimerized at ambient conditions in air
• Enantioselectivities are outstanding for various reaction paradigms
• Hydrogenations proceed under mild reaction conditions
• Low catalyst loadings yield high TONs

引用

Fang P and Hou XL. "Asymmetric Copper-Catalyzed Propargylic Substitution Reaction of Propargylic Acetates with Enamines." Organic letters 11.20 (2009): 4612-4615.

Imamoto T, et al. "Highly enantioselective hydrosilylation of simple ketones catalyzed by rhodium complexes of P-chiral diphosphine ligands bearing tert-butylmethylphosphino groups." Tetrahedron: Asymmetry 17(4) (2006): 560-565.

Yahav-Levi A, et al. "Aryl-bromide reductive elimination from an isolated Pt (IV) complex." Chemical Communications 46(19) (2010): 3324-3326.

法律資訊

QuinoxP is a registered trademark of Nippon Chemical Industry Co., Ltd.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301,H315,H319,H335,H413
• 防範說明: P273 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 3 Oral - Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Faceshields, Gloves