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品質等級
化驗
97%
折射率
n20/D 1.517 (lit.)
bp
195 °C (lit.)
密度
1.247 g/mL at 25 °C (lit.)
官能基
fluoro
SMILES 字串
COc1cc(F)ccc1O
InChI
1S/C7H7FO2/c1-10-7-4-5(8)2-3-6(7)9/h2-4,9H,1H3
InChI 密鑰
OULGLTLTWBZBLO-UHFFFAOYSA-N
一般說明
4-Fluoro-2-methoxyphenol is a fluorinated methoxy-substituted catechol analog.
應用
4-Fluoro-2-methoxyphenol may be used in the synthesis of:
- 4-halo-masked o-benzoquinones (MOBs)
- fluorinated masked o-benzoquinone
- poly(4-fluoro-2-methoxyphenol)
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
214.9 °F - closed cup
閃點(°C)
101.6 °C - closed cup
個人防護裝備
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Diels-Alder reactions of halogenated masked o-benzoquinones: synthesis of halogen-substituted bicyclo [2.2. 2] octenones.
Tetrahedron Letters, 50(7), 773-775 (2009)
European journal of pharmacology, 660(2-3), 445-453 (2011-04-19)
Apocynin, a methoxy-substituted catechol (4-hydroxy-3-methoxyacetophenone), originally extracted from the roots of Picrorhiza kurroa, has been extensively used as a non-toxic inhibitor of the multienzymatic complex NADPH oxidase. We discovered that the analogous methoxy-substituted catechol, 4-Fluoro-2-methoxyphenol (F-apocynin), in which the acetyl
Novel photoconductive polyfluorophenol synthesized by an enzyme.
Journal of Molecular Catalysis. B, Enzymatic, 72(1), 25-27 (2011)
A fluorinated masked o-benzoquinone.
Journal of Fluorine Chemistry, 125(12), 1965-1966 (2007)
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 42(7), 673-681 (1991-01-01)
The synthesis of 4-[18F]fluoroguaiacol (4-[18F]fluoro-2-methoxyphenol) has been achieved in no-carrier-added form starting from 2-methoxy-4-nitrobenzaldehyde, using nucleophilic aromatic substitution by [18F]fluoride followed by Baeyer-Villiger oxidation of the benzaldehyde to the phenol. Demethylation with boron tribromide gave 4-[18F]fluorocatechol (1,2-dihydroxy-4-[18F]fluorobenzene) with an overall
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