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化驗
97%
折射率
n20/D 1.417 (lit.)
bp
110 °C (lit.)
密度
1.27 g/mL at 25 °C (lit.)
官能基
fluoro
SMILES 字串
FC(F)(F)c1ccncc1
InChI
1S/C6H4F3N/c7-6(8,9)5-1-3-10-4-2-5/h1-4H
InChI 密鑰
IIYVNMXPYWIJBL-UHFFFAOYSA-N
一般說明
4-（三氟甲基）吡啶是吡啶衍生物。它可以通过 4-碘苯的三氟甲基化来制备。
應用
4-（三氟甲基）吡啶可用于以下反应：
- 通过金属化反应制备（三氟甲基）吡啶基锂。
- 金属有机骨架（MOF）的合成。
- 甲硫氰酸盐的合成。
訊號詞
Danger
危險分類
Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
68.0 °F - closed cup
閃點（°C）
20 °C - closed cup
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
其他客户在看
Manfred Schlosser et al.
Chemical Society reviews, 36(7), 1161-1172 (2007-06-20)
Pyridines carrying heterosubstituents (such as carboxy, amido, amino, alkoxy or trifluoromethyl groups or solely individual halogen atoms) can be readily and site selectively metalated. Subsequent reaction with a suitable electrophile opens rational access to a wealth of new building blocks
Fluorinated pyridine derivatives: Part 1. The synthesis of some mono-and bis-quaternary pyridine salts of potential use in the treatment of nerve agent poisoning.
Timperley CM, et al.
Journal of Fluorine Chemistry, 126(8), 1160-1165 (2005)
Enhancement of CO2/N2 selectivity in a metal-organic framework by cavity modification.
Bae YS, et al.
Journal of Materials Chemistry, 19(15), 2131-2134 (2009)
Copper-mediated trifluoromethylation of heteroaromatic compounds by trifluoromethyl sulfonium salts.
Cheng-Pan Zhang et al.
Angewandte Chemie (International ed. in English), 50(8), 1896-1900 (2011-02-18)
Malcolm E Tessensohn et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 18(16), 2250-2257 (2017-06-14)
The voltammetric behavior of 2,3,5,6-tetramethyl-1,4-phenylenediamine was found to be able to differentiate the hydrogen acceptor abilities of electroinactive pyridine compounds in acetonitrile. Weak and strong hydrogen acceptors were distinguished through the onset of a third oxidation process that came about
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