480142

4-苯氧基苯硼酸

≥95.0%

• 线性分子式: C₆H₅OC₆H₄B(OH)₂
• CAS号: 51067-38-0
• 分子量: 214.02
• MDL號碼: MFCD00093312
• 分類程式碼代碼: 12352103
• PubChem物質ID: 24871550
• NACRES: NA.22

属性

• 品質等級: 100
• 化驗: ≥95.0%
• mp: 141-145 °C (lit.)
• 官能基: phenoxy
• SMILES 字串: OB(O)c1ccc(Oc2ccccc2)cc1
• InChI: 1S/C12H11BO3/c14-13(15)10-6-8-12(9-7-10)16-11-4-2-1-3-5-11/h1-9,14-15H
• InChI 密鑰: KFXUHRXGLWUOJT-UHFFFAOYSA-N

说明

應用

4-Phenoxyphenylboronic acid can be used as a reactant:

• In the Suzuki-Miyaura coupling reaction to synthesize aryl derivatives via C-C bond formation by reacting with different aryl halides over a palladium catalyst.
• To prepare 1-phenoxy-4-(trifluoromethyl)benzene via oxidative trifluoromethylation using Chan-Lam-type reaction conditions.
• To synthesize evobrutinib, a potent Bruton′s tyrosine kinase (BTK) inhibitor.

其他說明

含有不定量的酸酐

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)