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Merck

477222

Sigma-Aldrich

4-氯苯胺

purified by sublimation, ≥99%

别名:

1-Amino-4-chlorobenzene, 4-Chlorophenylamine, p-Chloroaniline

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About This Item

线性分子式:
ClC6H4NH2
CAS号:
分子量:
127.57
Beilstein:
471359
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

蒸汽密度

4.4 (vs air)

蒸汽壓力

0.15 mmHg ( 25 °C)

化驗

≥99%

形狀

crystals
powder
solid

純化經由

sublimation

bp

232 °C (lit.)

mp

67-70 °C (lit.)

SMILES 字串

Nc1ccc(Cl)cc1

InChI

1S/C6H6ClN/c7-5-1-3-6(8)4-2-5/h1-4H,8H2

InChI 密鑰

QSNSCYSYFYORTR-UHFFFAOYSA-N

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一般說明

4-氯苯胺(4-CLA)是一种氯化芳香胺,在苯脲和苯氨基甲酸酯的微生物分解过程中作为中间体形成。已经报告了在含有氧化还原酶的水溶液中通过4-CLA与愈创木酚的聚合形成各种低聚物。4-CLA通过土壤真菌尖孢镰刀菌的氧化而分解。

應用

4-氯苯胺可被用于合成:
  • 4-氯亚硝基苯
  • 2-溴-4-氯苯胺
  • 2,6-二溴-4-氯苯胺

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Skin Sens. 1

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

248.0 °F - closed cup

閃點(°C)

120.0 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Oxidative co-oligomerization of guaiacol and 4-chloroaniline.
Simmons KE, et al.
Environmental Science & Technology, 23(1), 115-121 (1989)
The action of chloride peroxidase on 4-chloroaniline. N-oxidation and ring halogenation.
Corbett MD, et al.
The Biochemical Journal, 187(3), 893-903 (1980)
Microbial oxidation of 4-chloroaniline.
D D Kaufman et al.
Journal of agricultural and food chemistry, 21(1), 127-132 (1973-01-01)
M D Corbett et al.
The Biochemical journal, 175(2), 353-360 (1978-11-01)
The incubation of 4-chloroaniline with chloroperoxidase and H2O2 resulted in a rapid formation of 4-chloronitrosobenzene. This enzymic oxidation displayed a pH optimum at 4.4 with a Km of 8.1x10(-4)M and catalytic-centre activity of 312. The initial rate of the reaction
D Mortenson et al.
International endodontic journal, 45(9), 878-882 (2012-04-11)
To determine if the formation of para-chloroaniline (PCA) can be avoided by using an alternative irrigant following sodium hypochlorite but before chlorhexidine. Fifty-five single-rooted teeth were decoronated, instrumented to size 40, .06 taper whilst being irrigated with 14% ethylene-diamine-tetra-acetic acid

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