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Merck

428426

Sigma-Aldrich

(2-溴乙氧基)-叔丁基二甲基硅烷

99%

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About This Item

线性分子式:
BrCH2CH2OSi(CH3)2C(CH3)3
CAS号:
分子量:
239.23
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

99%

形狀

liquid

包含

Na2CO3 as stabilizer

折射率

n20/D 1.444 (lit.)

bp

70-75 °C/2.5 mmHg (lit.)

密度

1.115 g/mL at 25 °C (lit.)

官能基

bromo

儲存溫度

2-8°C

SMILES 字串

CC(C)(C)[Si](C)(C)OCCBr

InChI

1S/C8H19BrOSi/c1-8(2,3)11(4,5)10-7-6-9/h6-7H2,1-5H3

InChI 密鑰

JBKINHFZTVLNEM-UHFFFAOYSA-N

一般說明

(2-溴乙氧基)-叔丁基二甲基硅烷是一种硅烷衍生物。

應用

(2-溴乙氧基)--丁基二甲基硅烷用于 4-(3-羟丙基)-4'-甲基-2,2'-联吡啶的合成。
可用作 5-哌嗪-1-基-1 H -吲哚和(1 H -吲哚-2-基)-哌嗪-1-基-甲酮的选择性 N -烷基化试剂 ,也可用于合成 2-[3-[[(3,4,5-三甲氧基苯基)硫代]-1 H -吲哚-5-氧基] 乙醇。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

163.4 °F - closed cup

閃點(°C)

73 °C - closed cup


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Cyril Bressy et al.
Journal of the American Chemical Society, 127(38), 13148-13149 (2005-09-22)
A norbornene-mediated palladium-catalyzed tandem alkylation/C-H functionalization sequence is described, in which an alkyl-aryl bond and a heteroaryl-aryl bond are formed in one pot. A variety of highly substituted six- and seven-membered ring annulated indoles were synthesized in good yields from
Hansen, Joshua; et al.
Tetrahedron Letters, 47(1), 69-72 (2005)
Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies.
La Regina G, et al.
Journal of Medicinal Chemistry, 50(12), 2865-2874 (2007)
Tetrahedron Letters, 47, 69-69 (2006)
Mark Johnson et al.
Journal of medicinal chemistry, 55(12), 5826-5840 (2012-05-31)
In our effort to develop multifunctional drugs against Parkinson's disease, a structure-activity-relationship study was carried out based on our hybrid molecular template targeting D2/D3 receptors. Competitive binding with [(3)H]spiroperidol was used to evaluate affinity (K(i)) of test compounds. Functional activity

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