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形狀
solid
品質等級
成份
Dye content, ≥95%
mp
232-234 °C (lit.)
λmax
780 nm
SMILES 字串
[I-].CCCN1c2ccccc2C(C)(C)/C1=C\C=C3/CCCC(\C=C\C4=[N+](CCC)c5ccccc5C4(C)C)=C3Cl
InChI
1S/C36H44ClN2.HI/c1-7-24-38-30-18-11-9-16-28(30)35(3,4)32(38)22-20-26-14-13-15-27(34(26)37)21-23-33-36(5,6)29-17-10-12-19-31(29)39(33)25-8-2;/h9-12,16-23H,7-8,13-15,24-25H2,1-6H3;1H/q+1;/p-1
InChI 密鑰
IRPKBYJYVJOQHQ-UHFFFAOYSA-M
一般說明
IR-780碘化物是一种近红外亲脂性阳离子七甲胺荧光染料。它具有良好的荧光强度,可用作光热疗法治疗剂。这种成分表现出了780 nm的光吸收光谱,因而在医学治疗应用中被用作声动力学治疗剂。
應用
基于IR-780的染料有望用于生物医学应用和药物递送,支持肿瘤成像和靶向治疗。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Sentinel lymph node mapping by a near-infrared fluorescent heptamethine dye
Biomaterials, 31(7), 1911-1917 (2010)
Preferential accumulation of the near infrared heptamethine dye IR-780 in the mitochondria of drug-resistant lung cancer cells
Biomaterials, 35(13), 4116-4124 (2014)
IR-780 dye as a sonosensitizer for sonodynamic therapy of breast tumor
Scientific Reports, 6(28), 25968-25968 (2016)
IR-780 dye loaded tumor targeting theranostic nanoparticles for NIR imaging and photothermal therapy
Biomaterials, 34(28), 6853-6861 (2013)
Scientific reports, 5, 14713-14713 (2015-10-02)
The effectiveness of systemic rheumatoid arthritis (RA) treatments is limited by difficulties in achieving therapeutic doses within articular joints. We evaluated the ability of intra-articular administration of injectable formulations to synergistically enhance repair of RA joints. Methotrexate-loaded hyaluronic acid (Met-HA)
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