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Merck

380474

Sigma-Aldrich

2-羟乙基二硫化物

technical grade

别名:

2,2′-二硫二乙醇, 双(2-羟乙基)二硫代

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About This Item

线性分子式:
HOCH2CH2SSCH2CH2OH
CAS号:
分子量:
154.25
Beilstein:
1735851
EC號碼:
MDL號碼:
分類程式碼代碼:
12162002
PubChem物質ID:
NACRES:
NA.23

等級

technical grade

品質等級

形狀

liquid

折射率

n20/D 1.57 (lit.)

bp

158-163 °C/3.5 mmHg (lit.)

mp

25-27 °C (lit.)

密度

1.261 g/mL at 25 °C (lit.)

SMILES 字串

OCCSSCCO

InChI

1S/C4H10O2S2/c5-1-3-7-8-4-2-6/h5-6H,1-4H2

InChI 密鑰

KYNFOMQIXZUKRK-UHFFFAOYSA-N

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一般說明

2-羟乙基二硫化物(HEDS)是一种有机硫化合物,属于​二烷基二硫化物类,其中的两个羟乙基之间存在-S-S- 键。在材料科学中,HEDS可作为前体用于在金表面形成自组装单层(SAM),应用包括防腐蚀、润滑和传感器。此外,2-羟乙基二硫化物也用作有机合成中的还原剂,以及橡胶化合物生产中的交联剂。

應用

双(2-羟乙基)二硫化物可用作:
  • 扩链剂,用于制备水性自修复聚氨酯,作为皮革涂饰。
  • 前体,用于合成多功能引发剂,用于苯乙烯经原子转移自由基聚合为星形聚苯乙烯。
  • 起始材料,用于制备二硫化物支化剂。该支化剂可用于合成高度分支的聚甲基丙烯酸羟丙酯。

象形圖

CorrosionSkull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Eye Dam. 1

儲存類別代碼

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

233.6 °F - closed cup

閃點(°C)

112 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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African trypanosomes encode three monothiol glutaredoxins (1-C-Grx1 to 3). 1-C-Grx1 has a putative CAYS active site and Cys181 as single additional cysteine. The recombinant protein forms non-covalent homodimers. As observed for other monothiol glutaredoxins, Trypanosoma brucei 1-C-Grx1 was not active
I S Ayene et al.
International journal of radiation biology, 76(11), 1523-1531 (2000-12-01)
We investigated the effect of protein- and non protein-thiol oxidation on DNA double-strand-break (DSB) rejoining after irradiation and its relevance in the survival of CHO cells. We used mutant cells null for glucose 6 phosphate dehydrogenase (G6PD) activity since reducing
H Nakamura et al.
Free radical biology & medicine, 24(7-8), 1176-1186 (1998-06-17)
Thioredoxin (Trx) and glutaredoxin (Grx) are both multifunctional redox-active proteins. In this study, Grx was identified in human plasma by immunoaffinity purification. The affinity-purified material from human plasma displayed a band of 12 kDa identical to recombinant human Grx by
Iraimoudi S Ayene et al.
The Journal of biological chemistry, 277(12), 9929-9935 (2002-01-15)
Glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme of the oxidative pentose phosphate cycle, regulates the NADPH/NADP(+) ratio in eukaryotic cells. G6PD deficiency is one of the most common mutations in humans and is known to cause health problems for hundreds of
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FEBS letters, 511(1-3), 145-149 (2002-02-01)
Six mutants (Y26A, C27S, Y29F, Y29P, C30S and Y26W/Y29P) have been engineered in order to explore the active site of poplar glutaredoxin (Grx) (Y26CPYC30). The cysteinic mutants indicate that Cys 27 is the primary nucleophile. Phe is a good substitute

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Over the past two decades, the rapid advance of controlled living polymerization (CLP) techniques.

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