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Merck

359688

Sigma-Aldrich

Boc-Lys-OH

99%

别名:

Nα-(叔丁氧羰基)-L-赖氨酸, Nα-Boc-L-赖氨酸

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About This Item

线性分子式:
NH2(CH2)4CH(COOH)NHCOOC(CH3)3
CAS号:
分子量:
246.30
Beilstein:
4252546
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

99%

形狀

solid

光學活性

[α]20/D +22°, c = 2 in methanol

反應適用性

reaction type: Boc solid-phase peptide synthesis

mp

~205 °C (dec.) (lit.)

應用

peptide synthesis

SMILES 字串

CC(C)(C)OC(=O)N[C@@H](CCCCN)C(O)=O

InChI

1S/C11H22N2O4/c1-11(2,3)17-10(16)13-8(9(14)15)6-4-5-7-12/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m0/s1

InChI 密鑰

DQUHYEDEGRNAFO-QMMMGPOBSA-N

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應用

Boc-Lys-OH(Nα-叔丁氧羰基-L-赖氨酸)可作为构建单元用于合成:
  • 作为生物标记试剂,应用于基于异三功能肽的连接体分子。
  • 合成氮杂环和蒽醌的赖氨酸衍生物。
  • Boc-Lys(Bn4-DTPA)-OH,作为前体合成含肽的二乙基三胺五乙酸(DTPA)。
  • 二茂铁-氨基酸共轭物,用于开发化学战剂(CWA)传感器。

取代透過

产品编号
说明
价格

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Synthesis of Nα-Boc-Nε-tetrabenzyl-DTPA-l-lysine and Nα-Fmoc-Nε-tetra-t-butyl-DTPA-l-lysine, building blocks for solid phase synthesis of DTPA-containing peptides
Davies JS and Al-Jamri L
Journal of Peptide Science, 8(12), 663-670 (2002)
A novel heterotrifunctional peptide-based cross-linking reagent for facile access to bioconjugates. Applications to peptide fluorescent labelling and immobilisation
Clave G, et al.
Organic & Biomolecular Chemistry, 6(17), 3065-3078 (2008)
Synthesis of lysine derivatives containing aza-crown ethers and a chromophore unit
Ossowski T, et al.
Tetrahedron Letters, 46(10), 1735-1738 (2005)
Carla Kühn et al.
Journal of agricultural and food chemistry, 66(26), 6727-6733 (2018-06-09)
Glucosinolates and their breakdown products, especially isothiocyanates (ITCs), are hypothesized to exert a broad range of bioactivities. However, physiological mechanisms are not yet completely understood. In this study, formation of protein conjugates after incubation with benzyl isothiocyanate (BITC) was investigated
Carla Kühn et al.
Molecular nutrition & food research, 62(20), e1800588-e1800588 (2018-08-10)
Different metabolic and excretion pathways of the benzyl glucosinolate breakdown products benzyl isothiocyanate and benzyl cyanide are investigated to obtain information about their multiple fate after ingestion. Detailed focus is on the so far underestimated transformation/excretion pathways-protein conjugation and exhalation.

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