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349631

Sigma-Aldrich

2-酮戊二酸二甲酯

96%

别名:

α-酮戊二酸二甲酯

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About This Item

线性分子式:
CH3O2CCH2CH2COCO2CH3
CAS号:
13192-04-6
分子量:
174.15
MDL號碼:
MFCD00048052
分類程式碼代碼:
12352100
PubChem物質ID:
24861693
NACRES:
NA.22

化驗

96%

形狀

liquid

折射率

n20/D 1.439 (lit.)

bp

90-95 °C/0.4 mmHg (lit.)

密度

1.203 g/mL at 25 °C (lit.)

官能基

ester
ketone

SMILES 字串

COC(=O)CCC(=O)C(=O)OC

InChI

1S/C7H10O5/c1-11-6(9)4-3-5(8)7(10)12-2/h3-4H2,1-2H3

InChI 密鑰

TXIXSLPEABAEHP-UHFFFAOYSA-N

相关类别

一般說明

2-氧戊二酸二甲酯是在Krebs循环期间形成的关键中间体，并且是生物代谢途径中的重要氮转运子。2-氧戊二酸二甲酯的电化学行为已通过循环伏安法、方波伏安法和使用玻碳电极的差分脉冲伏安法进行了研究。

應用

2-氧代戊二酸二甲酯可以与双亲核物，如1,2-苯二胺、2-氨基苯酚和2-氨基苯硫醇，进行环缩合以形成新的杂环。
2-氧戊二酸二甲酯可用于合成构象受限的PNA（肽核酸）单体，该单体能够在三重基序中结合胸腺嘧啶。它可以通过与硝基苯乙烯的高度立体选择性Michael加成反应,合成4-芳基红藻氨酸类似物。

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
STBD7573V
STBF1024V
STBD6981V
STBD5556V
STBD1443V

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