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等級
for chiral derivatization
品質等級
蒸汽密度
2 (vs air)
蒸汽壓力
180 mmHg ( 20 °C)
形狀
liquid
濃度
18 mM in acetone
折射率
n20/D 1.3602
密度
0.79 g/mL at 25 °C
官能基
chloro
儲存溫度
2-8°C
InChI
1S/C16H13ClO2/c1-10(19-16(17)18)15-13-8-4-2-6-11(13)12-7-3-5-9-14(12)15/h2-10,15H,1H3
InChI 密鑰
SFRVOKMRHPQYGE-UHFFFAOYSA-N
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一般說明
(+)-1-(9-芴基)乙基氯甲酸酯是高度荧光的化合物 1,通常用作手性衍生剂,用在进行反相 HPLC 分析之前分离外消旋体。
應用
- β-甲基氨基丙氨酸(BMAA)对映体的手性分析:详细介绍了氯甲酸(+)-1--9-芴基乙酯(FLEC)的衍生化和随后的LC-MS/MS分析,增进了我们对氨基酸′立体化学的理解 (Zurita et al., 2019)。
- DL-氨基酸的对映选择性胶束电动色谱:利用氯甲酸(+)-1--9-芴基乙酯进行衍生化,结合UV诱导的荧光检测进行氨基酸的分析,改善了分析方法(Prior et al., 2018)。
訊號詞
Danger
危險聲明
危險分類
Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3
標靶器官
Central nervous system
安全危害
儲存類別代碼
3 - Flammable liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
1.4 °F
閃點(°C)
-17 °C
其他客户在看
Reversed-phase high-performance liquid chromatographic analysis of atenolol enantiomers in plasma after chiral derivatization with (+)-1-(9-fluorenyl) ethyl chloroformate.
Journal of Chromatography. B, Biomedical Applications, 568(1), 239-245 (1991)
Journal of chromatography. A, 660(1-2), 351-358 (1994-02-04)
A sensitive and selective high-performance liquid chromatographic method for the determination of reboxetine enantiomers in human plasma was developed. Although two chiral centres are present in reboxetine, its stereospecific synthesis leads to two rather than four possible enantiomers. After extraction
Journal of chromatography, 652(1), 73-81 (1994-01-14)
A sensitive, stereoselective and rapid reversed-phase liquid chromatographic method for the determination of (SR)- and (RS)-mefloquine enantiomers in 100 microliters plasma and capillary blood collected on chromatographic paper is presented. The assay involves protein precipitation from plasma, liquid-liquid extraction of
Journal of chromatography. A, 1590, 80-87 (2019-01-15)
D-amino acids (AA) analysis is becoming more and more relevant for metabolomics, therefore new analytical tools need to be developed. A common approach to achieve AA enantioseparation is chiral derivatization. Among the chiral derivatization reagents, (+) or (-)-1-(9-fluorenyl) ethyl chloroformate
Journal of chromatography. A, 1467, 400-408 (2016-08-25)
In the context of bioanalytical method development, process automatization is nowadays a necessity in order to save time, improve method reliability and reduce costs. For the first time, a fully automatized micellar electrokinetic chromatography-mass spectrometry (MEKC-MS) method with in-capillary derivatization
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