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品質等級
化驗
95%
形狀
liquid
折射率
n20/D 1.373 (lit.)
bp
66-67 °C (lit.)
密度
0.87 g/mL at 25 °C (lit.)
官能基
O-nitroso
nitroso
儲存溫度
2-8°C
SMILES 字串
CC(C)CON=O
InChI
1S/C4H9NO2/c1-4(2)3-7-5-6/h4H,3H2,1-2H3
InChI 密鑰
APNSGVMLAYLYCT-UHFFFAOYSA-N
一般說明
亚硝酸异丁酯广泛用作室内除臭剂。这是一种流行的娱乐药物。
應用
亚硝酸异丁酯用于研究吸入剂诱导的免疫毒性。
訊號詞
Danger
危險分類
Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Flam. Liq. 2 - Muta. 2
儲存類別代碼
3 - Flammable liquids
水污染物質分類（WGK）
WGK 3
閃點（°F）
-5.8 °F - closed cup
閃點（°C）
-21 °C - closed cup
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
L S Soderberg et al.
Experimental hematology, 24(7), 848-853 (1996-06-01)
Isobutyl nitrite is representative of a group of inhalants abused primarily by male homosexuals; abuse of this drug may be a risk factor for AIDS or Kaposi's sarcoma. Using a 14-day exposure regimen, we previously reported that inhaled isobutyl nitrite
L S F Soderberg et al.
Toxicology letters, 152(1), 47-56 (2004-08-06)
Epidemiological studies have identified abuse of nitrite inhalants as an independent co-factor in HIV infection and in Kaposi's sarcoma (KS) in AIDS patients. In the present study we investigated the ability of macrophages from mice exposed to isobutyl nitrite to
S M Bradberry et al.
Journal of toxicology. Clinical toxicology, 32(2), 179-184 (1994-01-01)
Isobutyl nitrite is a popular recreational drug among both homosexuals and heterosexuals as it is alleged to enhance sexual pleasure and prolong orgasm. In contrast to the ingestion of this volatile nitrite, inhalation is associated only rarely with serious sequelae
Lee S F Soderberg et al.
Toxicology letters, 132(1), 37-45 (2002-06-27)
Nitrite inhalant abuse has been correlated with HIV and Kaposi's sarcoma. Mouse models of inhalant exposure show immunosuppression and loss of immune cells. In the present study, isobutyl nitrite caused a dose-dependent loss of viability of a macrophage cell line.
[Methemoglobinemia due to ingestion of isobutyl nitrite ('poppers')].
W G Zijlstra
Nederlands tijdschrift voor geneeskunde, 147(23), 1144-1144 (2003-06-26)
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