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品質等級
化驗
99%
形狀
liquid
光學活性
[α]20/D +14°, neat
折射率
n20/D 1.4345 (lit.)
bp
185-188 °C (lit.)
密度
1.258 g/mL at 20 °C (lit.)
官能基
carboxylic acid
chloro
SMILES 字串
C[C@@H](Cl)C(O)=O
InChI
1S/C3H5ClO2/c1-2(4)3(5)6/h2H,1H3,(H,5,6)/t2-/m1/s1
InChI 密鑰
GAWAYYRQGQZKCR-UWTATZPHSA-N
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應用
(R)-(+)-2-Chloropropionic acid can be used as a starting material in the synthesis of:
- Thiolactic acid, a key intermediate, which is used for the preparation of 2(R),5(S)-oxathiolanones by reacting with pivalaldehyde.
- (R)-2-chloropropionyl chloride, a key intermediate, which is utilized in the synthesis of (R)-4,5-dihydro-5-methylpyridazin-3(2H)-one derivative with pyrazolopyridine ring as a potential phosphodiesterase inhibitor.
- 2-Chloropropionamide derivatives as protein disulfide isomerase (PID) inhibitors.
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1A
儲存類別代碼
8A - Combustible corrosive hazardous materials
水污染物質分類(WGK)
WGK 3
閃點(°F)
213.8 °F - closed cup
閃點(°C)
101 °C - closed cup
個人防護裝備
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
The Journal of organic chemistry, 84(21), 14069-14091 (2019-09-20)
We provide a full account of our synthetic studies targeting the hexacyclic calyciphylline B-type alkaloids, a subfamily of the Daphniphyllum natural products. Following an initial set of synthetic strategies focused on constructing the piperidine core of the calyciphylline B-type framework
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