230715

正丁基锂 溶液

11.0 M in hexanes

• 别名: 1-丁基锂, n-BuLi, Butyl lithium, 丁基锂 溶液
• 线性分子式: CH₃(CH₂)₃Li
• CAS号: 109-72-8
• 分子量: 64.06
• Beilstein: 1209227
• MDL號碼: MFCD00009414
• 分類程式碼代碼: 12352103
• PubChem物質ID: 24853833
• NACRES: NA.22

属性

• 形狀: liquid
• 品質等級: 100
• 濃度: 11.0 M in hexanes
• 密度: 0.761 g/mL at 25 °C
• 儲存溫度: 2-8°C
• SMILES 字串: [Li]CCCC
• InChI: 1S/C4H9.Li/c1-3-4-2;/h1,3-4H2,2H3;
• InChI 密鑰: MZRVEZGGRBJDDB-UHFFFAOYSA-N

说明

一般說明

n-Butyllithium (n-BuLi) is an organolithium reagent commonly used as a strong base to form corresponding lithium salts by the deprotonation of nitrogen, oxygen, phosphorus, and carbon acids. Heterocyclic compounds, such as furans, thiophenes, oxazoles, pyrroles, etc, can be lithiated α to the ring heteroatom using n?BuLi. These lithiated salts reacting in situ with alkyl halides to obtain useful organic compounds by the formation of the C-C bond.

應用

n-BuLi can be used as a reagent for lithium-halogen exchange reactions. Synthesis of various other useful reagents such as lithium diisopropylamide (LDA) and diphenylphosphine is prepared by in situ reaction with n-BuLi . In the polymerization of dienes, it can be employed as an initiator.

包裝

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

法律資訊

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

安全信息

• 象形圖: GHS02,GHS08,GHS05,GHS07,GHS09
• 訊號詞: Danger
• 危險聲明: H225,H250,H260,H304,H314,H336,H361f,H372,H411
• 防範說明: P210 - P231 + P232 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P370 + P378
• 危險分類: Aquatic Chronic 2 - Asp. Tox. 1 - Eye Dam. 1 - Flam. Liq. 2 - Pyr. Liq. 1 - Repr. 2 - Skin Corr. 1B - STOT RE 1 Inhalation - STOT SE 3 - Water-react 1
• 標靶器官: Central nervous system, Nervous system
• 安全危害: EUH014
• 儲存類別代碼: 4.2 - Pyrophoric and self-heating hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: -7.6 °F - closed cup
• 閃點（°C）: -22 °C - closed cup
• 個人防護裝備: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter