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Merck

191884

Sigma-Aldrich

羟丙基纤维素

average Mw ~100,000, powder, 20 mesh particle size (99% through)

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12162002
NACRES:
NA.23

描述

biological oxygen demand (BOD) 14,000 ppm

形狀

powder

自燃溫度

752 °F

分子量

average Mw ~100,000

雜質

<5 wt. %

粒徑

20 mesh (99% through)

pH值

5.0-8.5

界面張力礦物油

12.5 dyn/cm, 0.1 wt. % in H2O (vs. mineral oil)

黏度

65-175 cP, 5 wt. % in H2O(25 °C, Brookfield, spindle #1) (30 rpm)(lit.)

溶解度

polar organic solvents: soluble

密度

0.5 g/mL at 25 °C (lit.)

InChI

1S/C12H20N2/c1-5-12(13)11-7-6-10(14(3)4)8-9(11)2/h6-8,12H,5,13H2,1-4H3

InChI 密鑰

RRHXDYJWVYFMKV-UHFFFAOYSA-N

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一般說明

羟丙基 纤维素(HPC)是由环氧丙烷和碱性纤维素 在高温高压下反应制备的中性多糖。它可溶 于水和许多极性有机溶剂。HPC 被广泛用作食品 添加剂和药物递送系统。

應用

羟丙基纤维素可 用于以下应用:
  • HPC 可溶 于有机溶剂,这使其适合于 制备用于电化学设备的聚合物凝胶电解质。HPC 的网络形成能力可以改善凝胶电解质的机械和电 学性能。
  • 电纺 羟丙基纤维素纳米纤维可用于开发 各种疏水性药物的药物递送系统。
  • 羟丙基纤维素与碳酸钠等泡腾剂相结合,可作为粘合剂和功能材料制备用于控制氧氟沙星释放的漂浮片。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Jeremiah F Kelleher et al.
AAPS PharmSciTech, 21(1), 23-23 (2019-12-14)
The development of oral solid dosage forms, such as tablets that contain a high dose of drug(s), requires polymers and other additives to be incorporated at low levels as possible, to keep the final tablet weight low, and, correspondingly, the
Daniela M Correia et al.
Materials (Basel, Switzerland), 13(10) (2020-05-21)
This study reports a versatile method for the development of cellulose nanocrystals (CNCs) and water-soluble cellulose derivatives (methyl cellulose (MC), hydroxypropyl cellulose (HPC), and sodium carboxymethyl cellulose (NaCMC)) films comprising the ionic liquid (IL) 2-hydroxy-ethyl-trimethylammonium dihydrogen phosphate ([Ch][DHP]) for actuator
Jianjun Yang et al.
International orthopaedics, 37(3), 515-521 (2012-11-28)
The aim of this study was to determine whether hydroxypropylcellulose (HPC) coating of polyethylene terephthalate (PET) artificial ligaments enhances graft osseointegration in the bone tunnel. Thirty New Zealand white rabbits underwent artificial ligament graft transplantation in the bilateral proximal tibia
Alexandre Monteiro et al.
Drug development and industrial pharmacy, 39(2), 266-283 (2012-04-17)
Nanoparticles of BCS Class II drugs are produced in wet stirred media mills operating in batch or recirculation mode with the goal of resolving the poor water-solubility issue. Scant information is available regarding the continuous production of drug nanoparticles via
Maya Fujiwara et al.
Chemical & pharmaceutical bulletin, 60(11), 1380-1386 (2012-11-06)
We evaluated models for predicting spray mist diameter suitable for scaling-up the fluidized bed granulation process. By precise selection of experimental conditions, we were able to identify a suitable prediction model that considers changes in binder solution, nozzle dimension, and

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