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品質等級
化驗
97%
形狀
solid
密度
1.233 g/mL at 25 °C (lit.)
官能基
nitro
SMILES 字串
COc1ccc(cc1)[N+]([O-])=O
InChI
1S/C7H7NO3/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3
InChI 密鑰
BNUHAJGCKIQFGE-UHFFFAOYSA-N
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一般說明
4-硝基苯甲醚可经过氢氧根离子光化学亲核芳香取代，形成4-甲氧基苯酚和4-硝基苯酚。
應用
使用4-硝基苯甲醚作为探针以确定 Kamlet-Taft溶剂参数Π*，以及在16-420°C温度范围内的高压和超临界水。 4-硝基苯甲醚被用作碳和能量补充剂，以用于分离 红球菌 。
生化／生理作用
4-硝基苯甲醚可被人肝脏微粒体经 O-去甲基化为4-硝基苯酚 。
訊號詞
Warning
危險聲明
危險分類
Aquatic Chronic 3 - Carc. 2
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類（WGK）
WGK 1
閃點（°F）
266.0 °F - closed cup
閃點（°C）
130 °C - closed cup
個人防護裝備
Eyeshields, Gloves
其他客户在看
Petr Klán et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 1(12), 1012-1016 (2003-03-29)
A temperature-sensitive photochemical nucleophilic aromatic substitution on 4-nitroanisole by a hydroxide ion in homogeneous solutions, in a two-phase system under phase-transfer catalysis conditions, and in the microwave field is reported. It was found that reaction regioselectivity dramatically changes with temperature
Song Chen et al.
Journal of economic entomology, 98(3), 943-946 (2005-07-19)
Cytochrome P450 monooxygenases are a major metabolic mechanism responsible for pyrethroid resistance in Helicoverpa armigera (Hübner) from Asia. Cytochrome P450-mediated O-demethylation activity toward p-nitroanisole (PNOD) of individual fourth instars was determined in five strains of H. armigera by using a
M S Romero-Cano et al.
Journal of controlled release : official journal of the Controlled Release Society, 82(1), 127-135 (2002-07-11)
The controlled release of 4-nitroanisole from polylactide nanoparticles with different morphologies is reported. Two theoretical equations have been used in an attempt to fit the experimental results. Good agreement between theory and experiment was found for short release time. The
V V Shumiantseva et al.
Voprosy meditsinskoi khimii, 44(4), 369-375 (1998-12-10)
Semisynthetic flavocytochromes, obtained by covalent binding of riboflavins with cytochrome P450 2B4, were able to catalyse H2O2-supported aniline p-hydroxylation, amidopyrine N-demethylation and p-nitroanisole O-dealkylation. Rates of these reactions were considerably higher than the rates of corresponding NAD(P)H-dependent reactions and comparable
H V Gelboin et al.
Biochemical pharmacology, 50(11), 1841-1850 (1995-11-27)
Cytochromes P450 3A3/4 are inordinately important P450 enzymes catalyzing the metabolism of a large variety of clinically useful drugs, steroids, and carcinogens. Two monoclonal antibodies, MAb 3-29-9 and MAb 275-1-2, were prepared to human P450 3A4 from mice immunized with
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