SNCA
synuclein, alpha (non A4 component of amyloid precursor)
别名:
NACP, PARK1, PARK4, PD1
物种:
Human SNCA (6622), Mouse Snca (20617), Rat Snca (29219), chicken SNCA (395393), Horse SNCA (100053270), domestic cat SNCA (101091694), dog SNCA (478478), cow SNCA (282857), sheep SNCA (100294604), domestic guinea pig Snca (100725375)
UniProtKB ID:
基因ID:
- Human(6622) Summary: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
- Mouse(20617) synuclein, alpha
- Rat(29219) synuclein, alpha (non A4 component of amyloid precursor)
- chicken(395393) synuclein, alpha (non A4 component of amyloid precursor)
- Horse(100053270) synuclein, alpha (non A4 component of amyloid precursor)
- domestic cat(101091694) synuclein, alpha (non A4 component of amyloid precursor)
- dog(478478) synuclein, alpha (non A4 component of amyloid precursor)
- cow(282857) synuclein, alpha (non A4 component of amyloid precursor)
- sheep(100294604) synuclein, alpha (non A4 component of amyloid precursor)
- domestic guinea pig(100725375) synuclein, alpha (non A4 component of amyloid precursor)
- naked mole-rat(101700039) synuclein, alpha (non A4 component of amyloid precursor)
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Antibodies
货号
说明
物种反应性
应用
Anti-phospho-α-synuclein (Ser129) Antibody, clone PS129, ,
物种反应性
bovine, human, mouse, porcine, rat
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-聚集α-突触核蛋白抗体，克隆5G4, clone 5G4, from mouse, purified by affinity chromatography,
物种反应性
human
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
抗-磷酸-α-突触核蛋白（Ser129）抗体，克隆81A, clone 81A, from mouse,
物种反应性
human, mouse
应用
electron microscopy
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
抗 α-突触核蛋白抗体，小鼠单克隆, clone Syn211, purified from hybridoma cell culture,
物种反应性
human, zebra finch
应用
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
抗α-突触核蛋白抗体，克隆Syn211, ascites fluid, clone Syn211, Upstate®,
物种反应性
human
应用
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Proteins
货号
说明
物种
α-突触核蛋白 人, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
物种
human
α-Synuclein A53T 人, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
物种
human
α-Synuclein E46K 人, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), lyophilized powder,
物种
human