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Merck

HCN4

hyperpolarization activated cyclic nucleotide-gated potassium channel 4

别名:
SSS2
物种:
UniProtKB ID:
基因ID:
  • Human(10021) Summary: This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008]
  • Mouse(330953) hyperpolarization-activated, cyclic nucleotide-gated K+ 4
  • Rat(59266) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • domestic guinea pig(100717049) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • naked mole-rat(101715130) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • sheep(101117337) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • Domestic Rabbit(100009452) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • Zebrafish(557843) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • cow(785689) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • domestic cat(101090363) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • dog(448794) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • chicken(427478) hyperpolarization activated cyclic nucleotide-gated potassium channel 4

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Antibodies

货号
说明
物种反应性
应用
Anti-HCN4 Antibody, Chemicon®, from rabbit,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
抗-HCN4抗体,克隆PG2-1A4, clone PG2-1A4, from rat,
物种反应性
mouse
应用
electron microscopy
immunofluorescence

immunohistochemistry

western blot
单克隆抗-HCN4 小鼠抗, clone S114-10, 1 mg/mL, purified immunoglobulin,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunohistochemistry

western blot
Anti-HCN4, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry
Anti-HCN4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

货号
说明
物种
Ivabradine hydrochloride, ≥98% (HPLC),
物种
human
Dronedarone hydrochloride, ≥98% (HPLC),
物种
human
Dronedarone hydrochloride, European Pharmacopoeia (EP) Reference Standard,
物种
human
Dronedarone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
物种
human