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Merck

GABRG3

gamma-aminobutyric acid (GABA) A receptor, gamma 3

别名:
物种:
UniProtKB ID:
基因ID:
  • Human(2567) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]
  • Mouse(14407) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
  • Rat(79211) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • domestic guinea pig(100729690) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • naked mole-rat(101712623) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • sheep(101108521) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • Zebrafish(567057) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • cow(613670) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • domestic cat(101094182) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • dog(488685) gamma-aminobutyric acid (GABA) A receptor, gamma 3
  • chicken(770097) gamma-aminobutyric acid (GABA) A receptor, gamma 3

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Small Molecule - Agonist

货号
说明
物种
眠尔通标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
Oxazepam, ,
物种
human
甲丙氨酯, United States Pharmacopeia (USP) Reference Standard,
物种
human
甲丙氨酯, analytical standard,
物种
human
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
咪达唑仑标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
地西泮标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
奥沙西泮标准液 溶液, 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
阿普唑仑标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
依托咪酯, >98% (HPLC), powder,
物种
human

Small Molecule - Antagonist

货号
说明
物种
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
物种
human
氟硝西泮标准液, ,
物种
human
氯硝西泮, powder,
物种
human, rat
Ganaxolone, ≥98% (HPLC), solid,
物种
human, mouse
地西泮, ,
物种
human, rat

Antibodies

货号
说明
物种反应性
应用
Anti-GABRG3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-GABRG3 antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
human
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GABRG3,
物种
human