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Merck

GABRA5

gamma-aminobutyric acid (GABA) A receptor, alpha 5

别名:
物种:
UniProtKB ID:
基因ID:
  • Human(2558) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
  • Mouse(110886) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
  • Rat(29707) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Zebrafish(799124) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • dog(488688) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • cow(523515) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Horse(100050880) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic cat(101090773) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • chicken(418684) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • sheep(101115159) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Domestic Rabbit(100340943) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • naked mole-rat(101712275) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic guinea pig(100729411) gamma-aminobutyric acid (GABA) A receptor, alpha 5

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Small Molecule - Agonist

货号
说明
物种
加波沙朵 盐酸盐, solid, ≥98% (HPLC),
物种
human
蝇蕈醇 氢溴酸盐, ≥98% (HPLC), solid,
物种
human
异去甲基槟榔次碱 盐酸盐, solid,
物种
human
Piperidine-4-sulfonic acid, ,
物种
human
眠尔通标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate, ≥93% (TLC), powder,
物种
human
5α-Pregnan-3α-ol-11,20-dione, powder, ≥98% (TLC),
物种
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
物种
human
反式-脱氢雄甾酮, ≥99%,
物种
human, rat
Zolpidem, ≥98% (HPLC), solid,
物种
human, rat

Small Molecule - Antagonist

货号
说明
物种
Ro 15-4513, solid,
物种
rat, human
Picrotoxin, powder,
物种
human
Pregnenolone sulfate sodium salt, ,
物种
human
SR-95531, ≥98% (HPLC), powder,
物种
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-GABA A Receptor α 5 Antibody, Chemicon®, from rabbit,
物种反应性
mouse, rat
应用
western blot
Anti-GABRA5 (ab2) antibody produced in rabbit, affinity isolated antibody,
物种反应性
guinea pig, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
Monoclonal Anti-GABA A Receptor antibody produced in mouse, clone S415-24,
物种反应性
human, mouse
应用
immunofluorescence
western blot
Anti-GABRA5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Monoclonal Anti-GABA A Receptor-Atto 594 antibody produced in mouse, clone S415-24,
物种反应性
human, mouse
应用
immunofluorescence
western blot

Small Molecule - Inhibitor

货号
说明
物种
NO-711 hydrochloride, ≥98% (HPLC),
物种
human
(±)-Vigabatrin, ,
物种
human
丙泊酚, 97%,
物种
human
托吡酯, United States Pharmacopeia (USP) Reference Standard,
物种
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human

Small Molecule - Ligand

货号
说明
物种
L-655,708, ≥98% (HPLC), powder,
物种
human
依托咪酯, >98% (HPLC), powder,
物种
human
Flumazenil, >99% (HPLC), solid,
物种
rat, human
卡马西平, powder,
物种
rat, human
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GABRA5,
物种
human