GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
别名:
ECA4, EJM, EJM5
物种:
Human GABRA1 (2554), Mouse Gabra1 (14394), Rat Gabra1 (29705), Zebrafish gabra1 (768183), dog GABRA1 (489143), domestic cat GABRA1 (100286792), chicken GABRA1 (374214), cow GABRA1 (780973), sheep GABRA1 (101117759), naked mole-rat Gabra1 (101719179)
UniProtKB ID:
基因ID:
- Human(2554) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(14394) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
- Rat(29705) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- Zebrafish(768183) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- dog(489143) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- domestic cat(100286792) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- chicken(374214) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- cow(780973) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- sheep(101117759) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- naked mole-rat(101719179) gamma-aminobutyric acid (GABA) A receptor, alpha 1
- domestic guinea pig(100721626) gamma-aminobutyric acid (GABA) A receptor, alpha 1
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Small Molecule - Agonist
Small Molecule - Allosteric Modulator
货号
说明
物种
唑吡坦标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
扎来普隆标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
Zolpidem for system suitability, CRS, European Pharmacopoeia (EP) Reference Standard,
物种
human
Small Molecule - Antagonist
Antibodies
货号
说明
物种反应性
应用
抗GABA抗体 兔抗, affinity isolated antibody, buffered aqueous solution,
物种反应性
drosophila, rat, wide range
应用
dot blot
immunohistochemistry
immunohistochemistry
单克隆抗- GABA 小鼠抗, clone GB-69, ascites fluid,
物种反应性
wide range
应用
ELISA
dot blot
immunofluorescence
immunohistochemistry
dot blot
immunofluorescence
immunohistochemistry
抗GABA A受体α1 链抗体（NT，克隆BD24）, clone BD24, Chemicon®, from mouse,
物种反应性
avian, bovine, human, pig
应用
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
抗-GABA A受体β2/3 抗体, clone 62-3G1, Upstate®, from mouse,
物种反应性
bovine, human, rat
应用
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Small Molecule - Ligand
Small Molecule - Mixed Agonist/Antagonist
货号
说明
物种
苯酚 溶液, Equilibrated with 10 mM Tris HCl, pH 8.0, 1 mM EDTA, BioReagent, for molecular biology,
物种
human
苯酚 溶液, BioReagent, Saturated with 0.01 M citrate buffer, pH 4.3 ± 0.2, for molecular biology,
物种
human