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G7772

Sigma-Aldrich

D-Glucose 6-phosphate solution

~1 M in H2O (approx. 260 mg per ml)

Synonym(s):

D(+)-Glucopyranose 6-phosphate, Robison ester

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About This Item

Empirical Formula (Hill Notation):
C6H13O9P
CAS Number:
56-73-5
Molecular Weight:
260.14
EC Number:
200-286-9
MDL number:
MFCD00136040
UNSPSC Code:
12352201
PubChem Substance ID:
24895321
NACRES:
NA.25

biological source

synthetic (inorganic)

Assay

≥99% (TLC)

form

liquid

concentration

~1 M in H2O (approx. 260 mg per ml)

technique(s)

thin layer chromatography (TLC): suitable

color

colorless

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC(COP(O)(O)=O)C(O)C(O)C(O)C=O

InChI

1S/C6H13O9P/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14/h1,3-6,8-11H,2H2,(H2,12,13,14)

InChI key

VFRROHXSMXFLSN-UHFFFAOYSA-N

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Related Categories

Application


  • Phosphonate and α-fluorophosphonate analogs of d-glucose 6-phosphate as active-site probes of 1l-myo-inositol 1-phosphate synthase.: This study explores phosphonate and α-fluorophosphonate analogs of d-glucose 6-phosphate, offering insights into their use as probes for understanding enzyme mechanisms, which could impact biochemical research methodologies (Ramos-Figueroa et al., 2023).

Biochem/physiol Actions

D-Glucose 6-phosphate binds and inhibits the activity of sarcoendoplasmic reticulum calcium ATPase in rat brains resulting in a decrease in the accumulation of calcium in the endoplasmic reticulum.

Linkage

Prepared from G 7879.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Fook-Choe Cheah et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(7), 3205-3210 (2014-03-19)
Erythrocytes require glucose-6-phosphate dehydrogenase (G6PD) to generate NADPH and protect themselves against hemolytic anemia induced by oxidative stress. Peroxiredoxin 2 (Prx2) is a major antioxidant enzyme that requires NADPH to recycle its oxidized (disulfide-bonded) form. Our aims were to determine
Tiffany R Bonnett et al.
Insect biochemistry and molecular biology, 42(12), 890-901 (2012-09-18)
Mountain pine beetles, Dendroctonus ponderosae Hopkins (Coleoptera: Curculionidae), are native to western North America, but have recently begun to expand their range across the Canadian Rocky Mountains. The requirement for larvae to withstand extremely cold winter temperatures and potentially toxic
Richard G Conway et al.
PloS one, 7(11), e50349-e50349 (2012-12-05)
(18)F-Fluorodeoxyglucose (FDG)-positron emission tomography (PET) imaging of atherosclerosis in the clinic is based on preferential accumulation of radioactive glucose analog in atherosclerotic plaques. FDG-PET is challenging in mouse models due to limited resolution and high cost. We aimed to quantify
Glucose-6-phosphate reduces calcium accumulation in rat brain endoplasmic reticulum.
Cole, JT.
Frontiers in Neuroscience, 5, 51-51 (2012)
Victor V Lemeshko
Biochimica et biophysica acta, 1838(5), 1362-1371 (2014-01-15)
The simplest mechanism of the generation of the mitochondrial outer membrane potential (OMP) by the VDAC (voltage-dependent anion channel)-hexokinase complex (VHC), suggested earlier, and by the VDAC-glucokinase complex (VGC), was computationally analyzed. Even at less than 4% of VDACs bound
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