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9-Aminoacridine

matrix substance for MALDI-MS, ≥99.5% (HPLC)

Synonym(s):

Aminacrine

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About This Item

Empirical Formula (Hill Notation):
C13H10N2
CAS Number:
Molecular Weight:
194.23
EC Number:
MDL number:
UNSPSC Code:
12000000
PubChem Substance ID:
NACRES:
NA.21

grade

matrix substance for MALDI-MS

Quality Level

Assay

≥99.5% (HPLC)

form

powder

analyte functional class(es)

metabolites

analyte chemical class(es)

lipids

technique(s)

MALDI-MS: suitable

impurities

≤0.05% sulfated ash

loss

≤10% loss on drying

mp

238-240 °C

cation traces

Ba: ≤5 mg/kg
Ca: ≤200 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Fe: ≤10 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES string

Nc1c2ccccc2nc3ccccc13

InChI

1S/C13H10N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H,(H2,14,15)

InChI key

XJGFWWJLMVZSIG-UHFFFAOYSA-N

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General description

9-Aminoacridine, an aminoacridine dye which acts as a potent mutagen in viruses and bacteria.

Application

A MALDI matrix exhibiting low background and good sensitivity in the analysis of low molecular weight anions, such as metabolites, in negative mode

related product

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Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Mutagen-nucleic acid intercalative binding: structure of a 9-aminoacridine: 5-iodocytidylyl (3'-5') guanosine crystalline complex.
Sakore, T. D., et al.
Proceedings of the National Academy of Sciences of the USA, 74.1, 188-192 (1977)
9-Aminoacridine as a matrix for negative mode matrix-assisted laser desorption/ionization
Vermillion-Salsbury, R. L. and Hercules, D. M.
Rapid Communications in Mass Spectrometry, 16, 1575-1581 (2002)
Daniel J Karst et al.
Biotechnology progress, 33(4), 879-890 (2016-12-21)
Perfusion cell culture processes allow the steady-state culture of mammalian cells at high viable cell density, which is beneficial for overall product yields and homogeneity of product quality in the manufacturing of therapeutic proteins. In this study, the extent of
Yusuke Muranishi et al.
Scientific reports, 9(1), 8916-8916 (2019-06-22)
Adenocarcinoma is the most common type of lung cancer, and can be classified into various histologic subtypes. However, little is known about the subtype-dependent variations in lipid metabolism processes. We performed dual lipidomic analyses using liquid chromatography-mass spectrometry (LC-MS) and
Characterization of galactosyl and lactosyl sulfatide species in human serum by MALDI-TOF mass spectrometry.
Atsushi Hori et al.
Annals of clinical biochemistry, 56(5), 574-582 (2019-05-01)

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