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α-Carotene

analytical standard

Synonym(s):

(+)-α-Carotene

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About This Item

Empirical Formula (Hill Notation):
C40H56
CAS Number:
Molecular Weight:
536.87
Beilstein:
3227603
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

Assay

≥97.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

183-185 °C

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

−20°C

SMILES string

CC(/C=C/[C@H]1C(C)=CCCC1(C)C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(\C=C\C2=C(C)CCCC2(C)C)C

InChI

1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-23,25-28,37H,15-16,24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+/t37-/m0/s1

InChI key

ANVAOWXLWRTKGA-NTXLUARGSA-N

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General description

α-Carotene is a tetraterpenoid pigment that belongs to the group of carotenoids. Along with β-carotene, it is regarded as a precursor to vitamin A and is responsible for the orange-red color of fruits and vegetables. It is also known to show anti-oxidant and anti-carcinogenic properties.

Application

The analytical standards can also be used as follows:
  • Simultaneous quantification of five carotenoids and two chlorophylls from soybean flour samples by reversed-phase high-performance liquid chromatographic (RP-HPLC) method combined with UV-Vis detector
  • Profiling of carotenoids and their isomers in different plant tissue samples by high-performance liquid chromatography (HPLC) using a C30 column and photodiode array (PDA) detection
  • Development and validation of a high-performance liquid chromatography-UV/Vis detection method for the determination of four carotenoids— α-carotene, β-carotene, α-cryptoxanthin, and β-cryptoxanthin, in oil obtained from P. conoideus
  • Multi-residue determination of carotenoids in two algal species, isolated from saline water by HPLC coupled with a photodiode array detector
  • Ultra-high performance supercritical fluid chromatography-mass spectrometry (UHPSFC-MS) method-based quantitative analysis of carotenoids in microalgae and rosehip extract samples

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Simultaneous determination of plasma retinol, alpha-tocopherol, lycopene, alpha-carotene, and beta-carotene by high-performance liquid chromatography.
Miller WK, et al.
Analytical Biochemistry, 138(2), 340-345 (1984)
M Murakoshi et al.
Cancer research, 52(23), 6583-6587 (1992-12-01)
Although beta-carotene has been considered to be a key cancer preventive agent in green and yellow vegetables, other types of carotenoids, such as alpha-carotene, may also contribute to anticarcinogenic action, since these carotenoids usually coexist with beta-carotene and are detectable
Beibei Duan et al.
Nutrients, 11(9) (2019-09-06)
Thirty-four samples of human milk (HM) collected from mothers in Korea were classified into three groups according to their fat content. The lutein + zeaxanthin, β-cryptoxanthin, β-carotene, lycopene, α-carotene, and fatty acids (FAs) present in the HM were quantitatively analyzed.
Sheryl S Aguilar et al.
Journal of the Academy of Nutrition and Dietetics, 114(8), 1174-1180 (2014-06-22)
Studies of adult subjects have found a strong correlation between serum carotenoids and skin carotenoids measured by resonance Raman spectroscopy (RRS). No published studies have examined correlations between skin and serum carotenoids among children. We aimed to validate skin RRS
Rachel E Kopec et al.
The Journal of nutrition, 144(8), 1158-1166 (2014-06-06)
Dietary lipids have been shown to increase bioavailability of provitamin A carotenoids from a single meal, but the effects of dietary lipids on conversion to vitamin A during absorption are essentially unknown. Based on previous animal studies, we hypothesized that

Protocols

Protocol for HPLC Analysis of Carotene Compounds on Ascentis® RP-Amide

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