219126

β-Butyrolactone

98%

• Synonym(s): beta-Butyrolactone, β-Methyl-β-propiolactone, 3-Hydroxybutyric acid β-lactone, 4-Methyl-2-oxetanone
• Empirical Formula (Hill Notation): C₄H₆O₂
• CAS Number: 3068-88-0
• Molecular Weight: 86.09
• EC Number: 221-330-3
• MDL number: MFCD00005170
• UNSPSC Code: 12352100
• PubChem Substance ID: 24853107
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: 98%
• refractive index: n20/D 1.411 (lit.)
• bp: 71-73 °C/29 mmHg (lit.)
• mp: −43.5 °C (lit.)
• density: 1.056 g/mL at 25 °C (lit.)
• SMILES string: CC1CC(=O)O1
• InChI: 1S/C4H6O2/c1-3-2-4(5)6-3/h3H,2H2,1H3
• InChI key: GSCLMSFRWBPUSK-UHFFFAOYSA-N

Description

General description

β-Butyrolactone undergoes ring opening polymerization in the presence of ethoxy-bridged dinuclear indium catalyst to yield biodegradable polyester poly(hydroxybutyrate). Polymerization of racemic β-butyrolactone in the presence of chiral initiators has been reported. It is versatile building block for organic synthesis.

Application

β-Butyrolactone was used in the preparation of (3-O-[oligo-(3-hydroxybutyrate ester)] fluorescein, fluorescein derivative of poly(3-hydroxybutyrate) via anionic polymerization.

Safety Information

• Pictograms: GHS02,GHS08,GHS07
• Signal Word: Warning
• Hazard Statements: H226,H315,H319,H351
• Precautionary Statements: P201 - P210 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 3
• Flash Point(F): 140.0 °F - closed cup
• Flash Point(C): 60 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves