58979C30
SUPELCOSIL™ LC-CN (3 µm) HPLC Columns
L × I.D. 3.3 cm × 3 mm, HPLC Column
Synonyme(s) :
Cyanopropyl HPLC Column
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About This Item
Code UNSPSC :
41115700
eCl@ss :
32110501
Nomenclature NACRES :
SB.52
Produits recommandés
product name
Colonne HPLC SUPELCOSIL™ LC-CN, 3 μm particle size, L × I.D. 3.3 cm × 3 mm
Matériaux
stainless steel column
Agence
suitable for USP L10
Gamme de produits
SUPELCOSIL™
Caractéristiques
endcapped
Fabricant/nom de marque
SUPELCOSIL™
Conditionnement
1 ea of
Ampleur du marquage
4% Carbon loading
Paramètres
≤70 °C temp. range
400 bar pressure (5801 psi)
Technique(s)
HPLC: suitable
L × D.I.
3.3 cm × 3 mm
Superficie
170 m2/g
Couverture de surface
surface coverage 3.5 μmol/m2
Matrice
silica gel, spherical particle platform
fully porous particle
Groupe de la matrice active
cyano phase
Taille des particules
3 μm
Dimension de pores
120 Å
Plage de pH
2-7.5
Application(s)
food and beverages
Technique de séparation
hydrophilic interaction (HILIC)
normal phase
reversed phase
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Catégories apparentées
Description générale
La phase LC-CN est souvent utilisée à la place de la silice parce qu′elle offre les avantages d′une phase gréffée (telle qu′une équilibration rapide, et une sensibilité moindre aux faibles variations de concentration en eau de la phase mobile). Plus souvent, néanmoins, les colonnes LC-CN sont utilisées avec des phases mobiles de phase inverse.
Application
- Validated Simple HPLC-UV Method for Mycophenolic Acid (MPA) Monitoring in Human Plasma. Internal Standardization: : This study presents a validated HPLC-UV method for monitoring Mycophenolic Acid in human plasma, emphasizing the role of internal standardization in accuracy and precision of the results. The SUPELCOSIL™ LC-CN HPLC column was utilized for its effective separation capabilities (Kunicki and Wróbel, 2021).
- An Improved HPLC Method for Therapeutic Drug Monitoring of Daunorubicin, Idarubicin, Doxorubicin, Epirubicin, and Their 13-Dihydro Metabolites in Human Plasma: This paper details an enhanced HPLC method for monitoring various anthracycline drugs in human plasma. The use of the SUPELCOSIL™ LC-CN HPLC column improved the detection and quantification of these drugs and their metabolites (Fogli et al., 1999).
- Analysis of Diltiazem and Desacetyldiltiazem in Serum by High-Performance Liquid Chromatography: This research focused on developing a precise HPLC method to analyze diltiazem and its metabolite in serum, employing the SUPELCOSIL™ LC-CN HPLC column for effective separation and detection (Paczkowski et al., 1995).
- High-Performance Liquid Chromatographic Method for the Determination of Eclanamine and Its N-Desmethyl and N,N-Didesmethyl Metabolites in Urine: This study describes a robust HPLC method for determining eclanamine and its metabolites in urine, utilizing the SUPELCOSIL™ LC-CN HPLC column for its high-resolution capabilities (Lakings et al., 1988).
Informations légales
SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
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S Fogli et al.
Therapeutic drug monitoring, 21(3), 367-375 (1999-06-12)
A single high-performance liquid chromatography (HPLC) method, suitable for the analysis of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites is validated in the present study. Preparation of plasma samples was performed by a first extraction of analytes with a
H Kataoka et al.
Journal of chromatography. B, Biomedical sciences and applications, 731(2), 353-359 (1999-10-08)
The technique of automated in-tube solid-phase microextraction (SPME) coupled with liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS) was evaluated for the determination of ranitidine. In-tube SPME is an extraction technique for organic compounds in aqueous samples, in which analytes are extracted
H Kataoka et al.
Journal of analytical toxicology, 24(4), 257-265 (2000-06-29)
A simple and rapid method for the determination of amphetamine, methamphetamine, and their 3,4-methylenedioxy derivatives in urine samples was developed using automated in-tube solid-phase microextraction (SPME) coupled with liquid chromatography-electrospray ionization mass spectrometry (LC-ESI-MS). In-tube SPME is an extraction technique
D Paczkowski et al.
Polish journal of pharmacology, 47(5), 429-434 (1995-09-01)
This paper describes a simple high-performance liquid chromatographic (HPLC) method for the determination of diltiazem and desacetyldiltiazem in human serum. After basic methyl-tert-butyl ether extraction and back-extraction with hydrochloric acid, the drug and its metabolite was injected into a Supelcosil
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