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V5639

Sigma-Aldrich

Anti-Versican V0/V1 Neo antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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About This Item

Numéro MDL:
MFCD07370544
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

200

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Espèces réactives

mouse, human, rat

Technique(s)

western blot: 1 μg/mL using mouse cumulus oocyte complexes

Numéro d'accès UniProt

P13611

Conditions d'expédition

dry ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... VCAN(1462)
mouse ... Vcan(13003)
rat ... Vcan(114122)

Immunogène

synthetic peptide corresponding to amino acid residues 436-441 from human versican protein. This sequence is completely conserved between human, mouse and rat.

Forme physique

Solution in phosphate buffered saline containing 1.0 mg/ml BSA and 0.05% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Consulter la Bibliothèque de documents

Ewa M Koźma et al.
Glycobiology, 21(10), 1301-1316 (2011-05-06)
Organ fibrosis is associated with excessive deposition of dermatan sulfate (DS) in the extracellular matrix (ECM) of the affected tissue. However, the significance of DS in fibrosis process is poorly known. Thus, we have analyzed both in vitro and in
Thomas N Wight
Current opinion in cell biology, 14(5), 617-623 (2002-09-17)
Versican is a large extracellular matrix proteoglycan that is present in a variety of tissues. Successful cloning of the gene in man, mouse, cow and chicken has revealed the existence of at least four splice variants of versican, which differ
Wang Sheng et al.
Molecular biology of the cell, 16(3), 1330-1340 (2005-01-07)
Versican is a large chondroitin sulfate proteoglycan belonging to the lectican family. Alternative splicing of versican generates at least four isoforms named V0, V1, V2, and V3. We have shown that the versican V1 isoform not only enhanced cell proliferation
Sabrina Cattaruzza et al.
The Journal of biological chemistry, 277(49), 47626-47635 (2002-09-11)
We have carried out a comprehensive molecular mapping of PG-M/versican isoforms V0-V3 in adult human tissues and have specifically investigated how the expression of these isoforms is regulated in endothelial cells in vitro. A survey of 21 representative tissues highlighted
Dingcheng Gao et al.
Cancer research, 72(6), 1384-1394 (2012-01-28)
Tumors systemically initiate metastatic niches in distant target metastatic organs. These niches, composed of bone marrow-derived hematopoietic cells, provide permissive conditions for future metastases. However, the mechanisms by which these cells mediate outgrowth of metastatic tumor cells are not completely

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