SAB4503968

Anti-phospho-PECAM-1 (pTyr⁷¹³) antibody produced in rabbit

affinity isolated antibody

• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 82 kDa
• Espèces réactives: rat, human, mouse
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:20000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• Numéro d'accès NCBI: P16284
• Numéro d'accès UniProt: P16284
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pTyr713)
• Informations sur le gène: human ... PECAM1(5175)

Description

Description générale

The platelet and endothelial cell adhesion molecule 1 (PECAM1) is also termed as cluster of differentiation 31 (CD31). It belongs to the immunoglobulin (Ig) superfamily. This gene codes for a 130kDa protein and is located on human chromosome 17. PECAM1 is expressed on the surface of circulating platelets, monocytes, neutrophils and selected T-cell subsets.

Immunogène

The antiserum was produced against synthesized peptide derived from human PECAM-1 around the phosphorylation site of Tyr713.

Immunogen Range: 686-735

Actions biochimiques/physiologiques

The platelet and endothelial cell adhesion molecule 1 (PECAM1) participates in leukocyte-endothelial interaction.This protein has a major role in the adhesion cascade leading to leukocyte extravasation during the inflammatory process. PECAM1 also plays a role during the development of T cell.

Caractéristiques et avantages

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Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable