SAB4501764
Anti-Lamin A antibody produced in rabbit
affinity isolated antibody
Synonyme(s) :
70 kDa lamin, LAMA, LMN1, LMNA
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About This Item
Produits recommandés
Source biologique
rabbit
Niveau de qualité
Conjugué
unconjugated
Forme d'anticorps
affinity isolated antibody
Type de produit anticorps
primary antibodies
Clone
polyclonal
Forme
buffered aqueous solution
Poids mol.
antigen 74 kDa
Espèces réactives
mouse, human, rat
Concentration
~1 mg/mL
Technique(s)
ELISA: 1:1000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
Numéro d'accès NCBI
Numéro d'accès UniProt
Conditions d'expédition
wet ice
Température de stockage
−20°C
Modification post-traductionnelle de la cible
unmodified
Informations sur le gène
human ... LMNA(4000)
Catégories apparentées
Description générale
Lamin A/C (LMNA) gene codes for lamin A and C. Lamin A/C is a nuclear intermediate filament protein. LMNA gene is mapped to human chromosome 1q22. Anti-Lamin A Antibody detects endogenous levels of total Lamin A protein.
Immunogène
The antiserum was produced against synthesized peptide derived from human Lamin A/C.
Immunogen Range: 361-410
Immunogen Range: 361-410
Application
Anti-Lamin A antibody produced in rabbit has been used in immunoblotting.
Actions biochimiques/physiologiques
Lamin A/C (LMNA) is involved in the structural organization of the nucleus. It modulates gene expression. It may play a role in osteoblastogenesis. Mutation in the LMNA gene is associated with muscle dystrophies, cardiomyopathies, lipodystrophies, and neuropathies. LMNA protein plays a vital role in cell cycle progression. It controls extracellular signal-regulated kinase (ERK)/mitogen-activated protein kinase (MAPK) and Wnt β-catenin pathway.
Caractéristiques et avantages
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Forme physique
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Code de la classe de stockage
10 - Combustible liquids
Classe de danger pour l'eau (WGK)
nwg
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Certificats d'analyse (COA)
Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".
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