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M0944

Sigma-Aldrich

Anti-Msx1 antibody produced in rabbit

affinity isolated antibody, ammonium sulfate suspension

Synonyme(s) :

Anti-HOX7, Anti-msh homeo box homolog 1 (Drosophila)

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About This Item

Numéro MDL:
MFCD07370403
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.43

Source biologique

rabbit

Niveau de qualité

100

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

ammonium sulfate suspension

Poids mol.

antigen 30.9 kDa

Espèces réactives

human, rodent

Technique(s)

immunohistochemistry: suitable
western blot: suitable

Numéro d'accès UniProt

P28360

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... MSX1(4487)
mouse ... Msx1(17701)
rat ... Msx1(81710)

Immunogène

synthetic peptide corresponding to human Msx1 (amino acids 42-52), conjugated to BSA.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Chromatin immunoprecipitation (1 paper)

Description de la cible

Msx1 encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves

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Minglian Zhao et al.
Molecular and cellular biology, 33(16), 3099-3112 (2013-06-12)
Improving the knowledge of disease-causing genes is a unique challenge in human health. Although it is known that genes causing similar diseases tend to lie close to one another in a network of protein-protein or functional interactions, the identification of
F Wehrhan et al.
Oral diseases, 17(4), 433-442 (2011-03-04)
Bone-destructive disease treatments include bisphosphonates and antibodies against receptor activator for nuclear factor κB ligand (aRANKL). Osteonecrosis of the jaw (ONJ) is a side-effect. Aetiopathology models failed to explain their restriction to the jaw. The osteoproliferative transcription factor Msx-1 is
Marcos S Simões-Costa et al.
PLoS genetics, 8(12), e1003142-e1003142 (2013-01-04)
The critical stem cell transcription factor FoxD3 is expressed by the premigratory and migrating neural crest, an embryonic stem cell population that forms diverse derivatives. Despite its important role in development and stem cell biology, little is known about what
Irfan Saadi et al.
Development (Cambridge, England), 140(13), 2697-2702 (2013-05-31)
Bmp4 expression is tightly regulated during embryonic tooth development, with early expression in the dental epithelial placode leading to later expression in the dental mesenchyme. Msx1 is among several transcription factors that are induced by epithelial Bmp4 and that, in
Marcos Simões-Costa et al.
Developmental cell, 34(5), 544-554 (2015-08-11)
Neural crest cells are induced at the neural plate border by the combined action of transcription factors and signaling molecules. Here, we show that Axud1, a downstream effector of Wnt signaling, represents a critical missing link that integrates signaling and
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