H0266
Hemoglobin A2, Ferrous Stabilized human
lyophilized powder
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About This Item
Numéro CAS:
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352202
eCl@ss :
42030116
Nomenclature NACRES :
NA.61
Produits recommandés
Source biologique
human
Niveau de qualité
Essai
97-100% (agarose gel electrophoresis)
Forme
lyophilized powder
Technique(s)
immunofluorescence: suitable
Adéquation
suitable for electrophoresis and chromatography standard
Numéro d'accès UniProt
Température de stockage
−20°C
Informations sur le gène
human ... HBA2(3040)
Description générale
Hemoglobin A2 (HBA2) is mapped to human chromosome 16p13.3. HBA2 is a minor hemoglobin component and comprises of two α and δ chains.
Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.
has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins).
Application
Hemoglobin A2 was used in the determination of fetal hemoglobin by time-resolved immunofluorometric assay.
Hemoglobin A2, Ferrous Stabilized human has been used as a reference in reversed-phase high-performance liquid chromatography for quantifying δ-globin elution profile. It has also been used as calibrator in isotope dilution mass spectrometry (IDMS) measurements.
Actions biochimiques/physiologiques
Elevated levels of Hemoglobin A2 (HBA2) is observed in patients with β-thalassemia trait.
Conditionnement
Package size indicates the amount of hemoglobin as determined by the procedure of Drabkin, D.L., J. Biol. Chem., 164, 703 (1946).
Reconstitution
When reconstituted with buffer, gives >90% ferrous hemoglobin.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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To screen immediate family members of thalassaemia patients for carrier identification and counselling. The cross-sectional study was conducted at an urban thalassaemia treatment and prevention centre in Karachi, Pakistan, from January to December 2008, and involved 188 siblings of 100
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A D Stephens
International journal of laboratory hematology, 35(1), 116-116 (2012-11-20)
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