H4131
Hemoglobin porcine
lyophilized powder
Synonyme(s) :
Hb
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About This Item
Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352202
eCl@ss :
42030116
Nomenclature NACRES :
NA.61
Produits recommandés
Source biologique
Porcine
Niveau de qualité
Forme
lyophilized powder
Solubilité
H2O: soluble 10 mg/mL
Température de stockage
2-8°C
Informations sur le gène
pig ... HBB(407066) , HBE1(407067)
Description générale
Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.
Application
Hemoglobin from porcine was used to test the role of the L-arginine/nitric oxide pathway in relaxation of isolated human penile cavernous tissue and circumflex veins. It was also used to study the role of nitric oxide in neurogenic vasodilation of porcine cerebral artery.
Actions biochimiques/physiologiques
The Fe2+/Fe3+ balance is a physiological indicator of blood oxygenation. Deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.
Oxygen transporter, NO scavenger
Attention
Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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Les clients ont également consulté
F Y Chen et al.
The Journal of pharmacology and experimental therapeutics, 265(1), 339-345 (1993-04-01)
A superfusion bioassay cascade, with porcine pial arteries as donor tissues and rabbit aortic rings as detector tissues, was used to examine the role of nitric oxide (NO) in cerebral nonadrenergic, noncholinergic neurogenic vasodilation. All arteries were mechanically denuded of
H J Kirkeby et al.
Acta physiologica Scandinavica, 149(3), 385-392 (1993-11-01)
In human penile corpus cavernosum strips, pre-contracted by noradrenaline, electrical stimulation of nerves evoked non-adrenergic, non-cholinergic (NANC) relaxant responses which could be inhibited by tetrodotoxin 10(-6) M, NG-nitro-L-arginine (L-NNA) 10(-7)-10(-4) M, and oxyhaemoglobin 10(-5) M, but not by methylene blue
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