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Key Documents

C5678

Sigma-Aldrich

Carboxyméthylcellulose sodium salt

low viscosity

Synonyme(s) :

Carboxyméthylcellulose de sodium

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About This Item

Numéro CAS:
Numéro MDL:
Code UNSPSC :
12352201
Nomenclature NACRES :
NA.25

Source biologique

synthetic (organic)

Niveau de qualité

Forme

powder

Couleur

light yellow

Plage de pH utile

(20 °C, 10 g/L, 68 °F neutral)

Viscosité

50-200 cP, 4 % in H2O(25 °C)

Pf

> 300.05  °C ((> 572.09 °F ))

Solubilité

water: soluble

Traces de cations

Na: 6.5-9.5%

Température de stockage

room temp

InChI

1S/C6H12O6.C2H4O2.Na/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4;/h1,3-6,8-12H,2H2;1H3,(H,3,4);

Clé InChI

DPXJVFZANSGRMM-UHFFFAOYSA-N

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Catégories apparentées

Description générale

This product is a low viscosity carboxymethylcellulose (CMC); the viscosity of a 4% solution in water at 25 oC is 50-200 centipoise (cps). The viscosity is both concentration and temperature dependent. As the temperature increases, the viscosity decreases. As the concentration increases, the viscosity increases. Low, medium and high viscosity carboxymethylcellulose (CMC) are all used as suspending agents. Low viscosity CMC is usually used in "thin" aqueous solutions. Medium viscosity CMC is used to make solutions that look like a syrup. High viscosity CMC is used to make a mixture, which resembles a cream or lotion.

Application

Soluble carboxymethylcelluloses (CM-cellulose; CMC) available in varying viscosities are used as viscosity modifiers (thickeners) to stabilize emulsions and as a chemical dispersants of oils and other carbon structures such as nanotubes. CMCs are used in the development of biostructures such as biofilms, emulsions and nanoparticles for drug delivery. Carboxymethylcellulose, low viscosity, may be used to make solutions the consistency of "thin" aqueous solutions.

Notes préparatoires

The product is soluble in water (40 mg/mL).The key to dissolving carboxymethylcellulose is to add the solid carefully to the water so that it is well dispersed (well-wetted). Adding the solid in portions may be necessary. Adding water to the dry solid produces a "clump" of solid that is very difficult to dissolve; the solid must be added to the water. Stir gently or shake intermittently; do not stir constantly with a magnetic stirring bar. High heat is not needed and may actually slow down the solubilization process. A mixing device, such as an impeller-type agitator which produces a vortex, would allow the powder to be drawn into the liquid, but it may produce some shearing.
The product is soluble in water (40 mg/mL).The key to dissolving carboxymethylcellulose is to add the solid carefully to the water so that it is well dispersed (well-wetted). Adding the solid in portions may be necessary. Adding water to the dry solid produces a "clump" of solid that is very difficult to dissolve; the solid must be added to the water. Stir gently or shake intermittently; do not stir constantly with a magnetic stirring bar. High heat is not needed and may actually slow down the solubilization process. A mixing device, such as an impeller-type agitator which produces a vortex, would allow the powder to be drawn into the liquid, but it may produce some shearing.

Under normal conditions, the effect of temperature on solutions of this product is reversible, so slight temperature variation has no permanent effect on viscosity. However, long periods of heating CMC solutions at high temperatures (autoclaving) will degrade the product and permanently reduce viscosity. CMC is therefore very difficult to sterilize. γ-Irradiation, like heating, will degrade CMC. High viscosity CMC is more adversely affected by autoclaving and irradiation than is low viscosity CMC. Filtering CMC solutions tends to leave a gel behind because the material is fibrous, so solutions cannot be sterile filtered.

Autres remarques

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


Certificats d'analyse (COA)

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Shigenobu Mitsuzawa et al.
Scientific reports, 7(1), 16320-16320 (2017-11-28)
The glycoside hydrolase family 7 (GH7) member cellobiohydrolase (CBH) is a key enzyme that degrades crystalline cellulose, an important structural component of plant cell walls. As GH7 CBH is a major component in the enzyme mixture used to degrade biomass
R Farenzena et al.
Journal of animal physiology and animal nutrition, 101(5), 1057-1066 (2016-07-28)
Two in vivo digestibility trials with sheep were conducted to identify the minimum period length of feeding a new diet to obtain reproducible values of nutritional variables onward and the minimum length of collection period as to obtain maximal precision for
C Philippeau et al.
Journal of dairy science, 100(4), 2637-2650 (2017-02-06)
This study investigated the effects of bacterial direct-fed microbials (DFM) on ruminal fermentation and microbial characteristics, methane (CH
Tim Wartewig et al.
Nature, 552(7683), 121-125 (2017-11-17)
T cell non-Hodgkin lymphomas are a heterogeneous group of highly aggressive malignancies with poor clinical outcomes. T cell lymphomas originate from peripheral T cells and are frequently characterized by genetic gain-of-function variants in T cell receptor (TCR) signalling molecules. Although
Vinay Khatri et al.
Biotechnology for biofuels, 11, 144-144 (2018-05-26)
Pretreatment of lignocellulosic biomass (LCB) is a key step for its efficient bioconversion into ethanol. Determining the best pretreatment and its parameters requires monitoring its impacts on the biomass material. Here, we used fluorescent protein-tagged carbohydrate-binding modules method (FTCM)-depletion assay

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