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Key Documents

Autres documents

A4626

Sigma-Aldrich

1-Acetyl-2-phenylhydrazine

≥98%

Synonyme(s) :

N-Acetyl-N′-phenylhydrazine, acetylphenylhydrazine

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About This Item

Formule linéaire :
CH3CONHNHC6H5
Numéro CAS:
114-83-0
Poids moléculaire :
150.18
Numéro CE :
204-055-3
Numéro MDL:
MFCD00008672
Code UNSPSC :
12352127
ID de substance PubChem :
24890888
Nomenclature NACRES :
NA.25

Niveau de qualité

100

Pureté

≥98%

Forme

(Powder with Chunk(s) or Crystals with Chunk(s))

Pf

128-131 °C (lit.)

Chaîne SMILES 

CC(=O)NNc1ccccc1

InChI

1S/C8H10N2O/c1-7(11)9-10-8-5-3-2-4-6-8/h2-6,10H,1H3,(H,9,11)

Clé InChI

UICBCXONCUFSOI-UHFFFAOYSA-N

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Application

1-Acetyl-2-phenylhydrazine (AcPhHZ) which reacts with oxyhaemoglobin to form free radicals may be used to induce haemolytic anaemia for studies of the hematopoietic system.

Actions biochimiques/physiologiques

1-Acetyl-2-phenylhydrazine (AcPhHZ) is a vascular tumor initiator used in experimental animal model.

Pictogrammes

Skull and crossbones
GHS06

Mention d'avertissement

Danger

Mentions de danger

H301

Classification des risques

Acute Tox. 3 Oral

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificats d'analyse (COA)

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2,4-Dinitrophenylhydrazine reagent grade, 97%

Sigma-Aldrich

D199303

2,4-Dinitrophenylhydrazine

R S Weinstein et al.
Journal of cell science, 94 ( Pt 3), 593-600 (1989-11-01)
An unusual form of red cells (called sequestrocytes) that circulate in the peripheral blood of patients with sickle cell anemia has been identified. In wetmount light microscopy preparations, sequestrocytes appear as massively vacuolated erythrocytes. We have shown by transmission electron
P Caprari et al.
Biochemical medicine and metabolic biology, 45(1), 16-27 (1991-02-01)
After in vitro treatment of normal, glucose-6-phosphate dehydrogenase-deficient or pyruvate kinase-deficient human erythrocytes with three different oxidizing agents, the extent of lipid peroxidative degradation and the alterations of membrane proteins were evaluated. Exposure to tert-butylhydroperoxide induced, most markedly in G6PD-
I Goto et al.
American journal of veterinary research, 54(4), 622-626 (1993-04-01)
To clarify the oxidant defense functions of reduced glutathione (GSH) in erythrocytes, the effect of GSH deficiency on in vitro oxidant defense was studied, using GSH-deficient sheep erythrocytes (low-GSH cells). The formation of Heinz bodies in low-GSH cells was higher
S Croci et al.
Biochimica et biophysica acta, 1568(1), 99-104 (2001-12-04)
The oxidative action of acetylphenylhydrazine (APH) on red blood cells obtained from healthy donors and from patients with breast cancer has been investigated by Mössbauer spectroscopy. Whole blood was incubated with APH for different time periods and the Mössbauer spectra
Min Zhu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(18), 2543-2547 (2012-01-20)
To investigate Siwu decoction and its composite drugs on the blood-deficiency model mice induced by acetylphenyhydrazine and cyclophosphamide. Acetylphenyhydrazine and cyclophosphamide were used to copy the blood-deficiency model mice. Automatic hematology analyzer was used to test the peripheral hemogram. Weighting
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