466R-1

SDHB (EP288) Rabbit Monoclonal Primary Antibody

• Synonyme(s) : Succinate dehydrogenase B
• Code UNSPSC : 12352203

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100; 500
• Conjugué: unconjugated
• Forme d'anticorps: culture supernatant
• Type de produit anticorps: primary antibodies
• Clone: EP288, monoclonal
• Description: For In Vitro Diagnostic Use in Select Regions
• Forme: buffered aqueous solution
• Espèces réactives: human
• Conditionnement: vial of 0.1 mL concentrate (466R-14); vial of 0.1 mL concentrate Research Use Only (466R-14-RUO); vial of 0.5 mL concentrate (466R-15); vial of 1.0 mL concentrate (466R-16); vial of 1.0 mL concentrate Research Use Only (466R-16-RUO); vial of 1.0 mL pre-dilute Research Use Only (466R-17-RUO); vial of 1.0 mL pre-dilute ready-to-use (466R-17); vial of 7.0 mL pre-dilute ready-to-use (466R-18); vial of 7.0 mL pre-dilute ready-to-use Research Use Only (466R-18-RUO)
• Fabricant/nom de marque: Cell Marque^™
• Technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)
• Isotype: IgG
• Contrôle: GIST
• Conditions d'expédition: wet ice
• Température de stockage: 2-8°C
• Visualisation: cytoplasmic
• Informations sur le gène: human ... SDHB(6390)

Description

Description générale

Succinate dehydrogenase B (SDHB) is an iron-sulfur subunit of mitochondrial complex II, a respiratory complex that catalyzes the oxidation of succinate in the mitochondrial membrane. Many cancers are generally positive for SDHB, including renal cell carcinomas (RCC) and gastrointestinal stromal tumors (GIST). However, a subset of RCC and GIST tumors that are associated with SDH mutations, Carney-Stratakis Syndrome or Carney Triad exhibit a loss of SDHB expression.

Qualité

IVD

IVD

IVD

RUO

Forme physique

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Notes préparatoires

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Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable