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Key Documents

319R-2

Sigma-Aldrich

Cytokeratin 19 (EP72) Rabbit Monoclonal Primary Antibody

Synonyme(s) :

40-kDa keratin intermediate filament, CK-19, CK19, K19, K1CS, KRT 19, cytokeratin-19, keratin 19, type 1, keratin, type 1, 40-kd, keratin-19

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About This Item

Code UNSPSC :
12352203

Source biologique

rabbit

Niveau de qualité

100
500

Conjugué

unconjugated

Forme d'anticorps

culture supernatant

Type de produit anticorps

primary antibodies

Clone

EP72, monoclonal

Description

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forme

buffered aqueous solution

Espèces réactives

human

Conditionnement

vial of 0.1 mL concentrate (319R-24)
vial of 0.1 mL concentrate Research Use Only (319R-24-RUO)
vial of 0.5 mL concentrate (319R-25)
vial of 1.0 mL concentrate (319R-26)
vial of 1.0 mL concentrate Research Use Only (319R-26-RUO)
vial of 1.0 mL pre-dilute Research Use Only (319R-27-RUO)
vial of 1.0 mL predilute ready-to-use (319R-27)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (319R-28-RUO)
vial of 7.0 mL predilute ready-to-use (319R-28)

Fabricant/nom de marque

Cell Marque™

Technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)

Isotype

IgG

Contrôle

bladder, colon, colon carcinoma, thyroid carcinoma

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Visualisation

cytoplasmic

Informations sur le gène

human ... KRT19(3880)

Catégories apparentées

Description générale

Anti-cytokeratin 19 reacts with epithelia and epithelial malignancies including carcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Anti-cytokeratin 19 is very useful in differentiation of hepatocellular carcinoma from intrahepatic cholangiocarcinoma, especially in a combination of cytokeratin 7, CAM5.2, Ber-EP4/MOC31, Hep Par-1 and TTF1. Another useful application is the identification of thyroid papillary carcinoma.

Qualité

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Liaison

Cytokeratin 19 Positive Control Slides, Product No. 319S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Forme physique

Predilute: diluted in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Concentrate: diluted in Phosphate Buffered Saline, pH 7.2, with 1% BSA and <0.1% Sodium Azide

Notes préparatoires

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Autres remarques

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Informations légales

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Juan Rosai
Tumori, 89(5), 517-519 (2004-02-12)
Immunohistochemical markers of thyroid tumors can be divided into two major categories: those related to the cell types and those related to the type of pathology. The most important markers in the first category are thyroglobulin and TTF-1 for follicular
Richa Jain et al.
Applied immunohistochemistry & molecular morphology : AIMM, 18(1), 9-15 (2009-12-04)
Cytokeratin immunostaining forms the bedrock of the immunohistochemical evaluation of tumors. Cytokeratin 19 (CK19) belongs to a family of keratins, which are normally expressed in the lining of the gastroenteropancreatic and hepatobiliary tracts. CK19 immunohistochemistry has been used successfully in
Leandro Luongo de Matos et al.
Diagnostic pathology, 7, 97-97 (2012-08-15)
To distinguish between malignant and benign lesions of the thyroid gland histological demonstration is often required since the fine-needle aspiration biopsy method applied pre-operatively has some limitations. In an attempt to improve diagnostic accuracy, markers using immunocytochemistry and immunohistochemistry techniques

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