12247

Oleuropein

≥98.0%

• Synonyme(s) : (2S,3E,4S)-3-Ethylidene-2-(β-D-glucopyranosyloxy)-3,4-dihydro-5-(methoxycarbonyl)-2H-pyran-4-acetic acid 2-(3,4-dihydroxyphenyl)ethyl ester
• Formule empirique (notation de Hill): C₂₅H₃₂O₁₃
• Numéro CAS: 32619-42-4
• Poids moléculaire : 540.51
• Numéro CE : 251-129-6
• Numéro MDL: MFCD16879008
• Code UNSPSC : 12352202
• ID de substance PubChem : 329749662
• Nomenclature NACRES : NA.32

Propriétés

• Pureté: ≥98.0%
• Impuretés: ≤5.0% water
• Application(s): metabolomics; vitamins, nutraceuticals, and natural products
• Chaîne SMILES: COC(=O)C1=CO[C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)\C(=C\C)[C@@H]1CC(=O)OCCc3ccc(O)c(O)c3
• InChI: 1S/C25H32O13/c1-3-13-14(9-19(29)35-7-6-12-4-5-16(27)17(28)8-12)15(23(33)34-2)11-36-24(13)38-25-22(32)21(31)20(30)18(10-26)37-25/h3-5,8,11,14,18,20-22,24-28,30-32H,6-7,9-10H2,1-2H3/b13-3+/t14-,18+,20+,21-,22+,24-,25-/m0/s1
• Clé InChI: RFWGABANNQMHMZ-ZCHJGGQASA-N

Description

Description générale

Oleuropein is the major secondary metabolite found in the olive leaf extract. It is a secoiridoid polyphenol with a structure comprising of a glycosylated ester of elenolic acid with hydroxytyrosol.

Application

Oleuropein has been used:

• as an anti-inflammatory and antioxidant agent in hepatic steatosis on high-fat diet (HFD) fed mice
• to evaluate protective effects and antioxidant properties on male reproductive function in mice
• to study its inhibitory effects on bacterial (E. coli) ATP synthase
• as an inhibitor of plasminogen activator inhibitor-1 (PAI-1) to test its effect on the proliferation of breast cancer cells

Actions biochimiques/physiologiques

Oleuropein has anti-cancer, antimicrobial, antiviral, anti-ischemic and hypolipidemic activities. It functions as a skin protectant and aids anti-aging. Oleuropein is also implicated in anti-platelet aggregation, hypotensive, anti-rheumatic, antipyretic, diuretic and vasodilatory effects. It reduces the risk of coronary artery diseases. Oleuropein has been shown to augment the secretion of noradrenaline and adrenaline in rat.

Conditionnement

Bottomless glass bottle. Contents are inside inserted fused cone.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable