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PHR1317

Supelco

Toluene

Residual Solvent, Pharmaceutical Secondary Standard, Certified Reference Material

Synonyme(s) :

Toluene

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About This Item

Formule linéaire :
C6H5CH3
Numéro CAS:
108-88-3
Poids moléculaire :
92.14
Numéro Beilstein :
635760
Numéro CE :
203-625-9
Numéro MDL:
MFCD00008512
Code UNSPSC :
41116107
ID de substance PubChem :
329823303
Nomenclature NACRES :
NA.24

product name

Toluène, Pharmaceutical Secondary Standard; Certified Reference Material

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

300

Agence

traceable to USP 1601805

Densité de vapeur

3.2 (vs air)

Pression de vapeur

22 mmHg ( 20 °C)
26 mmHg ( 25 °C)

CofA (certificat d'analyse)

current certificate can be downloaded

Température d'inflammation spontanée

997 °F

Limite d'explosivité

7 %

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Indice de réfraction

n/D 1.496 (lit.)

Point d'ébullition

110-111 °C (lit.)

Pf

-93 °C (lit.)

Densité

0.865 g/mL at 25 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

single component solution

Température de stockage

2-30°C

Chaîne SMILES 

Cc1ccccc1

InChI

1S/C7H8/c1-7-5-3-2-4-6-7/h2-6H,1H3

Clé InChI

YXFVVABEGXRONW-UHFFFAOYSA-N

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Catégories apparentées

Description générale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Residual Solvent – Toluene is a certified reference material for the screening and quantification of residual solvents. This CRM is a secondary pharmaceutical reference standard and is traceable and qualified against the corresponding pharmacopeial standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAC1709 in the slot below. This is an example certificate only and may not be the lot that you receive.

Pictogrammes

FlameHealth hazardExclamation mark
GHS02,GHS08,GHS07

Mention d'avertissement

Danger

Classification des risques

Aquatic Chronic 3 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3

Organes cibles

Central nervous system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

39.9 °F - closed cup

Point d'éclair (°C)

4.4 °C - closed cup

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
LRAD2282
LRAD3454
LRAC1709
LRAA9113
LRAA0676

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Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

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Christopher M Filley et al.
Journal of neuropathology and experimental neurology, 63(1), 1-12 (2004-01-30)
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Murat Yücel et al.
Neuroscience and biobehavioral reviews, 32(5), 910-926 (2008-05-06)
Organic solvent abuse is associated with increased risk for serious medical, neurological, and neuropsychological impairments. While animal research suggests that exposure to organic solvents (especially toluene) may be neurotoxic, much less is known about the consequences of long-term exposure in
Perrine Hoet et al.
Critical reviews in toxicology, 38(2), 127-170 (2008-02-09)
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Faraday discussions, 173, 287-296 (2014-12-04)
The photoinduced reactive oxygen species (ROS) generation from several water-soluble fullerenes was examined. Macromolecular or small molecular water-soluble fullerene complexes/derivatives were prepared and their (1)O(2) and O(2)˙(-) generation abilities were evaluated by ESR spin-trapping methods. As a result, efficient (1)O(2)
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