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H2904

Sigma-Aldrich

HistoChoice® Tissue Fixative

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About This Item

Code UNSPSC :
12352202
Nomenclature NACRES :
NA.47

Couleur

colorless

Niveau de qualité

Application(s)

hematology
histology

Température de stockage

room temp

Application

Designed for the molecular biologist. Specially formulated to preserve antigenic sites for antibody probes and nucleic acid sites for in situ hybridizations. Fixed sections do not require predigestion or other recovery procedures to make important sites available.

Qualité

Contains no formaldehyde, glutaraldehyde or mercury. Non-toxic

Informations légales

HistoChoice is a registered trademark of Amresco, Inc.

Pictogrammes

FlameHealth hazardExclamation mark

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Organes cibles

Respiratory system

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 3

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Michael E Titford et al.
Archives of pathology & laboratory medicine, 129(4), 502-506 (2005-03-30)
In 1987, the Formaldehyde Standard became law in the United States, alerting laboratory workers to the potential carcinogenicity of formaldehyde. As a result, a variety of proprietary fixatives were developed for use in surgical pathology. To assess histomorphology with different
M A Kacena et al.
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 79(5-6), 185-190 (2005-03-15)
We compared histochemical and immunohistochemical staining as well as fluorochrome labeling in murine bone specimens that were fixed with 10% neutral buffered formalin to those fixed with HistoChoice. We showed that sections from undecalcified tibiae fixed for 4 h in
J Melrose et al.
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 83(1), 47-53 (2008-06-24)
Histochoice is a proprietary nontoxic, non-cross-linking fixative designed by the manufacturer to replace formaldehyde based fixation protocols. We compared Histochoice and formalin fixation for several cartilaginous tissues including, articular and growth plate cartilage, meniscus and intervertebral disc. The tissues were
D G Vince et al.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology, 15(2), 119-129 (1997-01-01)
Formaldehyde fixatives have traditionally been used to preserve tissues as they impart excellent morphological preservation. Formaldehyde fixes tissue by cross linking, a process which can reduce the antigenicity of tissue and weakens the intensity of immunohistochemical stains. Preliminary studies have
Erik P Rader et al.
Aging cell, 17(5), e12816-e12816 (2018-07-12)
Snell dwarf mice (Pit1dw/dw ) exhibit deficiencies in growth hormone, prolactin, and thyroid stimulating hormone. Besides being an experimental model of hypopituitarism, these mice are long-lived (>40% lifespan extension) and utilized as a model of slowed/delayed aging. Whether this longevity

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