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H1009

Sigma-Aldrich

Peroxyde d'hydrogène solution

30 % (w/w) in H2O, contains stabilizer

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About This Item

Formule empirique (notation de Hill):
H2O2
Numéro CAS:
7722-84-1
Poids moléculaire :
34.01
Numéro Beilstein :
3587191
Numéro MDL:
MFCD00011333
Code UNSPSC :
12352304
ID de substance PubChem :
57654227

Pression de vapeur

23.3 mmHg ( 30 °C)

Niveau de qualité

200

Pureté

29.0-32.0% (titration)

Forme

liquid

Durée de conservation

~2 yr

Pertinence de la réaction

reagent type: oxidant

Concentration

30 % (w/w) in H2O

Technique(s)

cell based assay: suitable
immunohistochemistry: suitable

Densité

1.110 g/cm3

Adéquation

suitable for DNA precipitation

Application(s)

general analytical
pharmaceutical

Température de stockage

2-8°C

Chaîne SMILES 

OO

InChI

1S/H2O2/c1-2/h1-2H

Clé InChI

MHAJPDPJQMAIIY-UHFFFAOYSA-N

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Catégories apparentées

Description générale

Hydrogen peroxide (H2O2), a topical antiseptic, is synthesized in aerobic cells as a byproduct of aerobic respiration. It might also be produced as an output of enzymatic reactions in peroxisomes, mitochondria, or other cell compartments.

Application

Hydrogen peroxide solution has been used:
  • to treat nasal epithelial cells for H2O2 sensitivity assays
  • to treat the human immortal keratinocyte cell line (HaCaT) and the human melanoma cell line (GLL19) to induce senescence
  • to incubate brain sections for bromodeoxyuridine (BrdU)/NeuN staining
  • in cell proliferation assay to incubate neural stem cells (NE-4C) for in vitro experiments

Actions biochimiques/physiologiques

Hydrogen peroxide (H2O2) is mainly used in wound cleaning. It can kill the pathogens through oxidation burst and by producing local oxygen. H2O2 functions as a signaling molecule or second messenger. It plays a key role in gene expression in numerous ways. H2O2 participates in modulating inflammation.

Caractéristiques et avantages

Ce composé figure sur la page Phosphoprotein Phosphatases (Tyrosine) du Handbook of Receptor Classification and Signal Transduction (manuel de classification des récepteurs et de transduction du signal). Pour parcourir d′autres pages du manuel, cliquez ici.

Autres remarques

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
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Pictogrammes

Corrosion
GHS05

Mention d'avertissement

Danger

Mentions de danger

H318 - H412

Classification des risques

Aquatic Chronic 3 - Eye Dam. 1

Code de la classe de stockage

5.1B - Oxidizing hazardous materials

Classe de danger pour l'eau (WGK)

WGK 1

Équipement de protection individuelle

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Sigma-Aldrich

386790-M

Peroxyde d'hydrogène solution

Peroxyde d'hydrogène 35%

SAFC

1.08600

Peroxyde d'hydrogène

Peroxyde d'hydrogène solution (stabilized) for synthesis

Sigma-Aldrich

8.22287

Peroxyde d'hydrogène solution

S V Lennon et al.
Cell proliferation, 24(2), 203-214 (1991-03-01)
Cell death may occur by either of two mechanisms: apoptosis or necrosis. Necrosis, the first type of cell death to be recognized, is an uncontrolled degenerative phenomenon invariably caused by noxious stimuli and is the result of irreversible failure of
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Scientific reports, 9(1), 11466-11466 (2019-08-09)
Pregnancy is a stress factor culminating into mild endoplasmic reticulum (ER) stress, which is necessary for placental development. However, excessive or chronic ER stress in pre-eclamptic placentas leads to placental dysfunction. The precise mechanisms through which excessive ER stress impacts
Stephen J D O'Keefe et al.
Nature communications, 6, 6342-6342 (2015-04-29)
Rates of colon cancer are much higher in African Americans (65:100,000) than in rural South Africans (<5:100,000). The higher rates are associated with higher animal protein and fat, and lower fibre consumption, higher colonic secondary bile acids, lower colonic short-chain
Shoichi Iriguchi et al.
Blood, 125(2), 370-382 (2014-10-29)
Although overexpression of T-bet, a master transcription factor in type-1 helper T lymphocytes, has been reported in several hematologic and immune diseases, its role in their pathogenesis is not fully understood. In the present study, we used transgenic model mice
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Investigative ophthalmology & visual science, 56(1), 538-543 (2015-01-13)
The purpose of the present study was to investigate the role of glutathione peroxidase 4 (GPx4) in conjunctival epithelial cells. An immortalized human conjunctival epithelial cell line was used. Cells were transfected with catalase, GPx1, GPx4, SOD1, SOD2, or control
Afficher tous les articles scientifiques apparentés

Articles

Colorimetric Detection of Western blot using 4-Chloro-1-Naphthol Solution Protocol

This solution is used as a substrate for detecting horseradish-peroxidase conjugates in Western blotting.

Protocoles

Enzymatic Assay of Catalase (EC 1.11.1.6)

This procedure may be used for all Catalase products.

Enzymatic Assay of Peroxidase (EC 1.11.1.7) 2,2'-Azino-bis(3-Ethylbenzthiazoline-6-Sulfonic Acid) as a Substrate

To standardize a procedure for the assay of Peroxidase using 2,2'-Azino-bis(3-Ethylbenzthiazoline-6-Sulfonic Acid) as a substrate.

Enzymatic Assay of Peroxidase (EC 1.11.1.7)

This procedure is for the determination of Peroxidase enzymatic activity using Pyrogallol as the substrate.

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