208694

Calmodulin, Bovine Brain, High Purity

Calmodulin is a ubiquitous Ca²⁺-binding protein that serves as a physiological effector of a wide range of biological processes. Purified from bovine brain.

• Synonyme(s) : Calmodulin, Bovine Brain, High Purity, CaM, Ca ²⁺/Calmodulin, CaM, Ca²⁺/Calmodulin
• Numéro CAS: 73298-54-1
• Numéro MDL: MFCD00131869
• Code UNSPSC : 12352202

Propriétés

• Niveau de qualité: 200
• Pureté: ≥95% (SDS-PAGE)
• Forme: lyophilized
• Activité spécifique: ≥250,000 units/mg protein
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Solubilité: aqueous buffer: soluble; water: soluble
• Conditions d'expédition: wet ice
• Température de stockage: −20°C

Description

Description générale

A ubiquitous Ca²⁺-binding protein distributed in eukaryotic cells that serves as a major physiological effector for a wide range of cellular responses. The Ca²⁺-calmodulin complex is involved in the maintenance of intracellular Ca²⁺ homeostasis, as well as in the regulation of the intracellular concentration of other second messengers, such as cyclic AMP and inositol trisphosphate. Calmodulin highly purified from bovine brain.



Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.

A ubiquitous Ca²⁺-binding protein that serves as a physiological effector of a wide range of biological processes. Calmodulin highly purified from bovine brain.

Note: this product cannot be used for animal treatment, in vivo research, or any contact procedure with livestock.

Conditionnement

Yes

Avertissement

Toxicity: Standard Handling (A)

Définition de l'unité

One unit is defined as the amount of calmodulin that gives rise to 50% of the maximal enzyme activation of a standard level of activator-deficient calcineurin.

Forme physique

Lyophilized from 30 mM HEPES, 1 mM CaCl₂, 0.1 mM DTT, pH 7.4.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C or -70°C). Aqueous stock solutions are stable for up to 2 months at -20°C or for up to 4 months at -70°C.

Please refer to the vial label for lot-specific reconstitution volume.

Autres remarques

Bagchi, I.C., et al. 1992. J. Biol. Chem.267, 3024.
O′Neil, K.T., and DeGrado, W.F. 1990. Trends Pharmacol. Sci. 15, 59.
Harrison, J.K., et al. 1988. J. Neurochem.51, 345.
Gopalakrishna, R., and Anderson, W.B. 1983. J. Biol. Chem.258, 2405.
Gopalakrishna, R., and Anderson, W.B. 1982. Biochem. Biophys. Res. Commun.104, 830.
Sharma, B.K., et al. 1979. Adv. Cyclic Nucleotide Res.10, 187.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3