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V-011

Supelco

Retinol solution

100 μg/mL ± 25% (Refer to COA) (Ethanol with 0.1% (w/v) BHT), ampule of 1 mL, reference material, Cerilliant®

Synonyme(s) :

Retinol solution, 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-2,4,6,8-nonatetraen-1-ol, Axerophthol, Vitamin A alcohol solution, Vitamin A1, all-trans-Retinol

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About This Item

Formule empirique (notation de Hill):
C20H30O
Numéro CAS:
68-26-8
Poids moléculaire :
286.45
Numéro Beilstein :
403040
Numéro MDL:
MFCD00001552
Code UNSPSC :
41116107
ID de substance PubChem :
329828922
Nomenclature NACRES :
NA.24

Qualité

reference material

Niveau de qualité

300

Forme

liquid

Caractéristiques

(Snap-N-Shoot®)
 (Snap-N-Spike®)

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

Concentration

100 μg/mL ± 25% (Refer to COA) (Ethanol with 0.1% (w/v) BHT)

Application(s)

clinical testing
clinical testing

Format

single component solution

Température de stockage

−70°C

Chaîne SMILES 

CC(=C/CO)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C

InChI

1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+

Clé InChI

FPIPGXGPPPQFEQ-OVSJKPMPSA-N

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Application

  • Enhancing cell culture systems: Research highlights the potential of Retinol as an essential component in cell culture systems, enhancing cell proliferation and differentiation. This supports its use in high-purity Retinol cell culture supplement applications (Ke et al., 2024).
  • Stabilized Retinol in dermatological applications: A study on topical 0.1% stabilized Bioactive Retinol demonstrates its efficacy and tolerability for treating photoaging, indicating its potential as a high-purity Retinol reagent for skin care research (Farris et al., 2024).
  • Drug-nutrient interaction research: Investigation into the interaction between Retinol and pharmaceuticals, like Acetylsalicylic Acid and Warfarin, provides insights into its role in vitamin-based assays, contributing to safer pharmacological studies involving Retinol-based assays (Renaud et al., 2024).
  • Assessment of Retinol signaling pathways: An in silico and in vitro approach examines natural ligands for receptors influenced by Retinol, aiding in the study of Retinol signaling pathways and its application as a research reagent in environmental safety (Choi et al., 2024).

Caractéristiques et avantages

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

FlameExclamation mark
GHS02,GHS07

Mention d'avertissement

Danger

Mentions de danger

H225,H319

Classification des risques

Eye Irrit. 2 - Flam. Liq. 2

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

57.2 °F

Point d'éclair (°C)

14.0 °C

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Sigma-Aldrich

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Sarmila Mazumder et al.
Lancet (London, England), 385(9975), 1333-1342 (2014-12-17)
Vitamin A supplementation in children aged 6 months to 5 years has been shown to reduce mortality. The efficacy of neonatal supplementation with vitamin A to reduce mortality in the first 6 months of life is plausible but not established.
Gretchen A Stevens et al.
The Lancet. Global health, 3(9), e528-e536 (2015-08-16)
Vitamin A deficiency is a risk factor for blindness and for mortality from measles and diarrhoea in children aged 6-59 months. We aimed to estimate trends in the prevalence of vitamin A deficiency between 1991 and 2013 and its mortality
Inong R Gunanti et al.
The Journal of nutrition, 144(4), 489-495 (2014-02-07)
Mexican-American children have a high prevalence of overweight/obesity. Micronutrient deficiencies may be contributing to the development of greater adiposity in these children. This study investigated the relations between adiposity and serum concentrations of carotenoids, retinol, and vitamin E among Mexican-American
Giuseppe Zanotti et al.
Vitamins and hormones, 69, 271-295 (2004-06-16)
Retinol-binding protein (RBP) is the retinol-specific transport protein present in plasma. The available crystal structures of different forms of RBP have provided details of the interactions of this binding protein with retinol, retinoids, and transthyretin (TTR, one of the plasma
Karen M Edmond et al.
Lancet (London, England), 385(9975), 1315-1323 (2014-12-17)
Results of randomised controlled trials of newborn (age 1-3 days) vitamin A supplementation have been inconclusive. The WHO is coordinating three large randomised trials in Ghana, India, and Tanzania (Neovita trials). We present the findings of the Neovita trial in
Afficher tous les articles scientifiques apparentés

Protocoles

HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

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