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Merck
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Documents

586846

Sigma-Aldrich

N-Benzoyladenosine

96%

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About This Item

Formule empirique (notation de Hill):
C17H17N5O5
Numéro CAS:
4546-55-8
Poids moléculaire :
371.35
Numéro Beilstein :
632501
Numéro MDL:
MFCD00056988
Code UNSPSC :
12352200
ID de substance PubChem :
24881135
Nomenclature NACRES :
NA.22

Pureté

96%

Forme

solid

Activité optique

[α]20/D -49°, c = 1% in DMSO

Pf

141-145 °C (lit.)

Chaîne SMILES 

OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NC(=O)c4ccccc4)ncnc23

InChI

1S/C17H17N5O5/c23-6-10-12(24)13(25)17(27-10)22-8-20-11-14(18-7-19-15(11)22)21-16(26)9-4-2-1-3-5-9/h1-5,7-8,10,12-13,17,23-25H,6H2,(H,18,19,21,26)/t10-,12-,13-,17-/m1/s1

Clé InChI

NZDWTKFDAUOODA-CNEMSGBDSA-N

Pictogrammes

Exclamation mark
GHS07

Mention d'avertissement

Warning

Mentions de danger

H302

Classification des risques

Acute Tox. 4 Oral

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Chun-Lei Zhang et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(46), 11114-11126 (2017-10-17)
Classical and systems genetics have identified wide networks of genes associated with cognitive and neurodevelopmental diseases. In parallel to deciphering the role of each of these genes in neuronal or synaptic function, evaluating the response of neuronal and molecular networks
Behzad Shariati et al.
Molecular and cellular neurosciences, 70, 54-67 (2015-11-26)
Guanine nucleotide exchange factors directly activated by cAMP (Epacs) have emerged as important signaling molecules mediating persistent hypersensitivity in animal models of inflammation, by augmenting the excitability of sensory neurons. Although Epacs activate numerous downstream signaling cascades, the intracellular signaling
Marlies Schippers et al.
The Journal of pharmacology and experimental therapeutics, 363(2), 126-135 (2017-09-03)
Exchange protein activated by cAMP (Epac-1) is an important signaling mechanism for cAMP-mediated effects, yet factors that change Epac-1 levels are unknown. Such factors are relevant because it has been postulated that Epac-1 directly affects fibrogenesis. Prostaglandin E
Shuying He et al.
The American journal of pathology, 188(6), 1374-1388 (2018-03-27)
Epithelial-to-mesenchymal transition (EMT) is a key contributor to fibroblast activation in fibrosis of multiple organs, including the intestine. Parathyroid hormone-like hormone (PTHLH) is an important factor in renal fibrosis and regulates several processes, including EMT. Herein, we investigated the role
Kevin W-H Lo et al.
Journal of tissue engineering and regenerative medicine, 10(10), 867-875 (2014-02-05)
Small molecule-based regenerative engineering is emerging as a promising strategy for regenerating bone tissue. Small molecule cAMP analogues have been proposed as novel biofactors for bone repair and regeneration and, while promising, the effect that these small molecules have on
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