383473
3-Formyl-6-methylchromone
97%
Synonyme(s) :
6-Methyl-4-oxo-4H-1-benzopyran-3-carboxaldehyde
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About This Item
Produits recommandés
Niveau de qualité
Pureté
97%
Forme
solid
Pf
172-173 °C (lit.)
Chaîne SMILES
Cc1ccc2OC=C(C=O)C(=O)c2c1
InChI
1S/C11H8O3/c1-7-2-3-10-9(4-7)11(13)8(5-12)6-14-10/h2-6H,1H3
Clé InChI
GBWMIOYSMWCYIZ-UHFFFAOYSA-N
Catégories apparentées
Description générale
3-Formyl-6-methylchromone is a 3-formyl-substituted chromone. The combustion calorimetric estimation of the enthalpy of combustion of 3-formyl-6-methylchromone has been reported. Its anti-proliferative action on the MDR human colon cancer and mouse lymphoma has been investigated.
Application
3-Formyl-6-methylchromone has been used for the synthesis of 3-formyl-6-methylchromone-4-phenylthiosemicarbazone.
3-Formyl-6-methylchromone may be used in the preparation of series of Schiff′s bases, via reaction with aromatic sulfonamides, such as sulfanilamide, homosulfanilamide, 4-aminoethyl-benzenesulfonamide, a pyrimidinyl-substituted sulfanilamide derivative, sulfaguanidine and 4-amino-6-trifluoromethyl-benzene-1,3-disulfonamide. It may be used in the preparation of Schiff base, which undergoes addition reaction with diethyl phosphite to afford bis[(1,2,4,3-triazaphospholyl)(chromonyl)aminomethylphosphonate] derivative and bis[(1,2,4,3-triazaphospholyl)(chromonyl)phosphorylamino-methylphosphonate] derivative.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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Les clients ont également consulté
Bioorganic & medicinal chemistry letters, 15(12), 3096-3101 (2005-05-24)
A series of Schiff's bases was prepared by reaction of 3-formyl-chromone or 6-methyl-3-formyl-chromone with aromatic sulfonamides, such as sulfanilamide, homosulfanilamide, 4-aminoethyl-benzenesulfonamide, a pyrimidinyl-substituted sulfanilamide derivative, sulfaguanidine and 4-amino-6-trifluoromethyl-benzene-1,3-disulfonamide. The zinc complexes of these sulfonamides have also been obtained. The new
Synthetic approach for novel bis (a-aminophosphonic acid) derivatives of chromone containing 1, 2, 4, 3-triazaphosphole moieties
Heteroatom Chem., 20(3), 117-122 (2009)
Synthesis, characterization, crystal structure and antimicrobial activity of copper (II) complexes with a thiosemicarbazone derived from 3-formyl-6-methylchromone.
Polyhedron, 81, 123-131 (2014)
Enthalpies of combustion and formation of 3-formylchromones.
Thermochimica Acta, 450(1), 35-37 (2006)
Journal of photochemistry and photobiology. B, Biology, 175, 178-191 (2017-09-12)
Two chromone hydrazone ligands HL
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