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Merck

TNNI3

troponin I type 3 (cardiac)

Synonymes:
CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI
Espèce(s):
Human TNNI3 (7137), Mouse Tnni3 (21954), Rat Tnni3 (29248), chicken TNNI3 (396428), domestic cat TNNI3 (493744), Horse TNNI3 (100034065), dog TNNI3 (403566), sheep TNNI3 (101121961), domestic guinea pig Tnni3 (100718375), naked mole-rat Tnni3 (101711288)
ID UniProtKB:
P19429
ID du gène:
  • Human(7137) Summary: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
  • Mouse(21954) troponin I, cardiac 3
  • Rat(29248) troponin I type 3 (cardiac)
  • chicken(396428) troponin I type 3 (cardiac)
  • domestic cat(493744) troponin I type 3 (cardiac)
  • Horse(100034065) troponin I type 3 (cardiac)
  • dog(403566) troponin I type 3 (cardiac)
  • sheep(101121961) troponin I type 3 (cardiac)
  • domestic guinea pig(100718375) troponin I type 3 (cardiac)
  • naked mole-rat(101711288) troponin I type 3 (cardiac)

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ELISA

Référence du produit
Description
Espèce(s)
RAB0634
Human TNNI3 / Troponin I, Cardiac Muscle ELISA Kit, ,
Espèce(s)
human

Small Molecule - Allosteric Modulator

Référence du produit
Description
Espèce(s)
L5545
Levosimendan, ≥98% (HPLC),
Espèce(s)
human

Antibodies

Référence du produit
Description
Espèces réactives
Application
HPA046428
Anti-TNNI3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
WH0007137M4
Monoclonal Anti-TNNI3 antibody produced in mouse, clone 1E7, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
western blot
MABT546
Anti-Troponin I Antibody, clone 5C11.1, clone 5C11.1, from mouse,
Espèces réactives
bovine, chicken, human, mouse, rat
Application
western blot
SAB2108732
Anti-TNNI3, affinity isolated antibody,
Espèces réactives
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
SAB4502991
Anti-TNNI3 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot

Proteins

Référence du produit
Description
Espèce(s)
T9924
Troponin I from human heart, lyophilized powder,
Espèce(s)
human

esiRNA

Référence du produit
Description
Espèce(s)
EHU022131
MISSION® esiRNA, targeting human TNNI3,
Espèce(s)
human
EMU068451
MISSION® esiRNA, targeting mouse Tnni3,
Espèce(s)
mouse